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Pharmaceutical, Drugs, Fine Chemicals, Bulk Drug Intermediates, Pharmaceutical Drugs, Pharma Drug Ingredients Intermediates, Drug Intermediates, Speciality Chemicals, Raw Materials, Fine and Specialty Chemicals Intermediates, Pharmaceutical Bulk Drugs

Indian drugs and pharmaceutical industry has advanced perceptibly and is getting ready  for the new patent regime and  to withstand global competition, which is expected to be unleashed by new winds of liberalisation - a new era of liberalisation - much different from what was ushered in since the conclusion of the Uruguay Round and the establishment of the World Trade Organisation.

The industry has been expanding at annual rates ranging between 8 to 10% (against global growth rate of 6%).  According to a study  by McKinsey, Vision 2010, the domestic pharmaceutical industry could attain a size of  $25 billion (Rs 1200 billion) by 2010 by focusing on two areas: first, innovation-led research, development and new drug discoveries; and second, information technology-led remote sales and marketing.  The market for bulk drugs and formulations had increased from about Rs 103  billion in 1990-91 to an estimated Rs 435  billion at the end of 2003-04.  The prices of Indian essential drugs are among the lowest in the world. Apart from strides made by the industry in the last half-a-century, lower production cost due to reverse engineering and low R&D outlays has been a major factor in keeping the prices under check.

The global pharmaceutical industry is estimated at $ 300 billion, not all representing cross-border trade.  India's measly share of $ 1.5 billion in global trade represents an untapped potential. Under the regime of economic liberalisation underway since early 1990s, the drugs and pharmaceutical sector witnessed initiatives at fresh investment in the sector. Nearly 1735 investment proposals of the order of around Rs 166  billion were initiated. The foreign collaboration proposals approved numbered around 425 with a foreign direct investment  (FDI) component of over Rs 25 billion. The pharmaceuticals have figured high on the export front. In 2001-02,  the sector was  estimated to have registered a growth of 17.6% at around Rs 20.3 billion.

In the wake of economic liberalisation, many a  overseas players  returned or contemplated returning to India. These include Ivox Corp (USA),  Taro Pharmaceuticals (Israel) and Merck (USA). These are out either to set shop or looking for acquisitions in India. Hexal AG of Germany has established a liaison office in India. MILLIONCs like Rocha, Bayer, Aventis and Chiron are making India a regional hub for bulk drugs. 

The Export Import Bank of India (Exim Bank) had  doubled its corpus for the pharmaceutical industry to Rs 2 billion as a result of increased activity in the industry, especially in the external sector. The fund is used for the development and commercialisation of the new products and applications, significant improvement in the existing design of  products, setting up and expansion of pilot plants, research studies for obtaining regulatory approvals, cost of filing and managing international patent and R&D Centres.

It needs, however, to be recognised that the presence  of small scale manufacturers has resulted, on the one hand,  in a highly fragmented industry, and on the other, it has made it possible to supply a near 100,000 drugs including vitamins, antibiotics, antibacterials, cardio-vascular and other essential drugs. These account for nearly 37% of the market.  While each of about 80% of the manufacturers has annual sales below a billion rupees, top ten companies are known to control over 30% of the market. At present there are more than 20,000 players in the country.

The major players are: Alembic Chem, Aurobindo Pharma, Cipla, Dr. Reddy's, FDC, IPCA Labs, Jagsonpal Pharma, J.B. Chemicals, Kopran, Lupin Labs, Lyka Labs, Morepan Labs, Nicholas Piramal, Ranbaxy Labs, Sun Pharma, Themis Medicare, GlaxoSmithkline, Astrazeneca, Aventis, E-Merck, Torrent Pharma, TTK Healthcare, Unichem Labs,  Wockhardt  and  Zandu Pharma.  Until recently, only a few of the Indian companies had gone into any serious R&D activity. Much of the effort was directed to affordable analogue research. The R&D level in the country is low with even well-placed pharma companies spending less than 2% of turnover on R&D. MILLIONCs are known to contribute as much as 10% or more of their turnover to R&D.  While India is very strong in process chemistry, biology and applied bio-chemistry, initiatives at all levels - government, academia, private sector - involving heavy financial outlays, are called for.

Ayurveda continues to remain a preferred system of medicine for a vast segment of population in the country. The country has over 400,000 registered practitioners of the Indian system of medicine. Around 170 institutes properly affiliated to various universities impart under- or post-graduate courses each year. These institutes churn out some 5,500 fresh practitioners. The practitioners are supported by 12,000 dispensaries and 2,100 beds available for ayurveda treatment countrywide. The emerging biotechnology sector has already taken by storm and is offering sops to states to make these as the thriving ground for the highly potential segment in medicare.

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Veterinary Medicines (Powder, Tablets & Capsules)

Veterinary medicine, also called veterinary science, medical specialty concerned with the prevention, control, diagnosis, and treatment of diseases affecting the health of domestic and wild animals and with the prevention of transmission of animal diseases to people. Veterinarians ensure a safe food supply for people by monitoring and maintaining the health of food-producing animals. Veterinary medicine is widely practiced, both with and without professional supervision. Veterinary medicine, which deals with prevention, diagnosis, and treatment of diseases, disorder, and injury in animals. Veterinary medicine is widely practiced worldwide due to increasing number of pet adoptions, rising veterinary expenditure, increasing number of veterinary professionals, and rising demand for pet insurance. The India Veterinary Healthcare market is expected to register a CAGR of around 10% during the forecast period, 2018 to 2023. Veterinary medicines are associated with treatment, diagnosis, and prevention of diseases among animals. It covers a variety of animal species, both, in domestic and wild. The global market for veterinary drugs has been categorized on the basis of geography into North America, Latin America, the Middle East and Africa, Asia Pacific, and Europe. Among these, North America is projected to experience a high growth in the next few years. As per the research study, this region led the global market in the last few years and is predicted to remain in the similar position throughout the forecast period. Furthermore, Europe is anticipated to experience a healthy growth in the next few years. Furthermore, the rising incidence of infectious disease among animals is expected to enhance the growth of the veterinary drugs market in Latin America and Asia Pacific. The rising popularity of a variety of companion animals and the growing demand for several meat products are considered as the key factors that are anticipated to encourage the growth of the global veterinary drugs market in the next few years. In addition to this, the growing disposable income of consumers, especially in developing economies has further allowed a significant rise in the expenditure on animal care, which is likely to accelerate the growth of the overall market in the near future.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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IV Fluids in Plastic Bottles (IV Solution Automatic System)

Intravenous fluids are fluids which are intended to be administered to a patient intravenously, directly through the circulatory system. These fluids must be sterile to protect patients from injury, and there are a number of different types available for use.The basic function of IV fluids is to replenish the body fluids.Intravenous fluids can also be used as a route of medication administration. The market for Intravenous (IV) Solution is expected to reach USD 11,511.2 million by 2022 and is expected to grow at a CAGR of 7.69% during the forecast period 2016-2022. The factors which drive the growth of the market are the rising prevalence of chronic diseases, rising acceptance of vitamin C intravenous treatment therapy to treat colorectal cancer.Entrepreneurs who invest in this project will be successful. Few Indian major players are as under • Abaris Healthcare Pvt. Ltd. • AhlconParenterals (India) Ltd. • AxaParenterals Ltd. • Infutec Healthcare Ltd. • Kokad Pharmaceutical Laboratories Ltd. • Parenteral Surgicals Ltd.
Plant capacity: IV Fluids (500 ml Bottle): 40000 Pcs./dayPlant & machinery: Rs. 2658 lakhs
Working capital: -T.C.I: Cost of Project: Rs10817 lakhs
Return: 17.00%Break even: 25.00%
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Microcrystalline Cellulose (Pharmaceutical Grade)

Microcrystalline cellulose (MCC) is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. The most common form is used in vitamin supplements or tablets. It is also used in plaque assays for counting viruses, as an alternative to carboxymethyl cellulose. Microcrystalline Cellulose Market size is projected to grow from USD 885.1 million in 2018 to USD 1,241.4 million by 2023, at a CAGR of 7.0% between 2018 and 2023 and is forecast to exceed USD 1.2 billion by 2024.Which facilitates the development of new technologies and ensure a high quality product.
Plant capacity: Microcrystalline Celluose (Pharmaceutical Grade): 5 MT/dayPlant & machinery: Rs 74 lakhs
Working capital: -T.C.I: Cost of Project: Rs 277 lakhs
Return: 29.00%Break even: 78.00%
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X-ray Films

X-ray film displays the radiographic image and consists of emulsion (single or double) of silver halide (silver bromide (AgBr) is most common) which when exposed to light, produces a silver ion (Ag+) and an electron. The electrons get attached to the sensitivity specks and attract the silver ion. X-ray films for general radiography consist of an emulsion-gelatin containing radiation sensitive silver halide crystals, such as silver bromide or silver chloride, and a flexible, transparent, blue-tinted base. The emulsion is different from those used in other types of photography films to account for the distinct characteristics of gamma rays and x-rays, but X-ray films are sensitive to light. The global X-ray film market is expected to register a CAGR of 5% over the forecast period of 2018–2023. In the medical industry, the usage of X-ray films in dental inspection, mammograms, and orthopedic inspection hold the major share in the market. The industrial sector has a long established usage of X-ray films and is widely used in NDT methods for volumetric examination radiography. The presence of X-ray machines in hospitals enables physicians in detection of somatic issues, as well as trauma. X-ray is very useful for detection and treatment of neurological problems, cancer, cardiac diseases and bone related problems. The existing pervasiveness of these issues will increase demand for the product over the forecast period.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Sulfamethoxazole

Sulfamethoxazole is an antibiotic. It is used for bacterial infections such as urinary tract infections, bronchitis, and prostatitis and is effective against both gram negative and positive bacteria such as Listeria monocytogenes and E. coli. Sulfamethoxazole is a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Ringer's Lactate Solution

Ringer's lactate solution (RL), also known as sodium lactate solution and Hartmann's solution, is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water. It is used for replacing fluids and electrolytes in those who have low blood volume or low blood pressure. It may also be used to treat metabolic acidosis in cases other than those caused by lactic acidosis and to wash the eye following a chemical burn. It is given by injection into a vein or applied to the affected area. Ringer’s lactate solution, or lactated Ringer’s solution, is a type of isotonic, crystalloid fluid further classified as a balanced or buffered solution used for fluid replacement. The contents of Ringer’s lactate include sodium, chloride, potassium, calcium, and lactate in the form of sodium lactate, mixed into a solution with an osmolarity of 273 mOsm/L and pH of about 6.5. In comparison, normal saline (NS) has an osmolarity of about 286 mOsm/L. Ringer Lactate R Solution is especially useful for the control of excessive vomiting, diarrhoea, dehydration or in infectious diseases such as cholera. It is administered either through an intravenous fluid injection or through a process known as electrolyte therapy.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Empty Hard Gelatin Capsules

Hard gelatin capsules are made of two shells: the capsule body and a shorter cap. They are clear, colorless, and essentially tasteless. Two-piece capsules have been used for almost a century in the pharmaceutical field and the gelatin has been adopted as the main material of these capsules due to its excellent characteristic as a gelatinizer. The global empty hard gelatin capsules market was valued at $1,841.5 million in 2017 and is expected to reach $3,707.5 million by 2025, registering a CAGR of 9.1% from 2018 to 2025. Capsules are relatively stable shells that contain or encapsulate medicines, which are administered in a variety of dosage forms. As a whole there is a good scope for new entrepreneur to invest in this business. Few Indian major players are as under • A B L Biotechnologies Ltd. • A C G Arts & Properties Pvt. Ltd. • Akums Drugs & Pharmaceuticals Ltd. • Capsugel Healthcare Ltd. • Chemcaps Ltd. • Dinesh Remedies Ltd.
Plant capacity: 2500 Th.Nos./ dayPlant & machinery: Rs 1565 lakhs
Working capital: -T.C.I: Cost of Project: Rs 2149 lakhs
Return: 28.00%Break even: 49.00%
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Saline and Dextrose Fluid (IV)

Saline is a general phrase referring to a sterile solution of sodium chloride in water, but is only sterile when it is to be placed parenterally; otherwise, a saline solution is a salt water solution. The sterile solution is typically used for intravenous infusion, rinsing contact lenses, nasal irrigation, and often used to clean a new piercing. Dextrose Solution (5%) is an isotonic solution and supplies calories to human body instantaneously without disturbing the electrotype balance. The global Intravenous (IV) solutions market was valued at USD 6.9 billion in 2015 and is projected to grow at a CAGR of 7.8% over the forecast period. And is expected to reach a value of USD 13.79 billion by 2024. As a whole there is a good scope for new entrepreneur to invest in this business. Few Indian major players are as under • Amanta Healthcare Ltd. • Axa Parenterals Ltd. • Infutec Healthcare Ltd. • Kokad Pharmaceutical Laboratories Ltd. • Parenteral Drugs (India) Ltd. • Parenteral Surgicals Ltd.
Plant capacity: Dextrose IV Fluid (100 ml Size) : 7800 Bottles/Day Dextrose-Sodium Chloride IV Fluid (250 ml Size): 7200 Bottles/Day Sodium Chloride IV Fluid (500 ml Size): 6200 Bottles/Day Ciprofloxacin (100 gm Size) Bye Product: 250 Bottles/Day FluconazolPlant & machinery: Rs 2281 lakhs
Working capital: -T.C.I: Cost of Project: Rs 3200 lakhs
Return: 28.00%Break even: 34.00%
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Empty Hard Gelatin Capsules Manufacturing Industry

Empty Hard Gelatin Capsules Manufacturing Industry. Production of Empty Gel Capsules. Pharmaceutical Capsule Manufacture Gelatin is considered to be animal proteins that are utilized to prepare capsules, which gives calculated quantities of products. Empty hard gelatin capsules are made from gelatin (Gelatin is a translucent, colorless, brittle (when dry), flavorless solid substance, derived from the collagen- an animal protein). Empty Hard Gelatin Capsules contain 12 – 16% moisture. But the moisture content can vary up on the storage conditions. Empty gelatin capsules are available in various colors and color combinations including transparent and metallic capsules. Widely demanded in food, cosmetics and pharmaceutical industry, Empty Hard Gelatin Capsules are used for strengthening bones, improving air quality and various other uses. It is used for filling the solid substance. Features: • Hermetically sealed and airtight • Increase the bio-availability of poorly soluble nutrients • Longer shelf life • Easily digested and dissolved within minutes • Safe to consume • Fast relief Advantage of Gelatin Capsules There are following importance of gelatin capsules: ? It is taste less, odorless and easy to administration. ? They are attractive to appearance. ? Easy to handle and carry. ? Drug having an unpleasant odor and placed in the closed shell. ? Rapid drug release possible. ? Flexibility of formulation • No need to form a compact that must stand up to handling. • Unique mixed fills possible. • Role in drug development. • Role in clinical tests. ? Sealed HGCs are good barriers to atmospheric oxygen. Market Outlook Indian EHGC market is estimated at approx 64 billion capsules in absolute production terms. The global empty capsules market was valued at $1,841.5 million in 2017 and is expected to reach $3,707.5 million by 2025, registering a CAGR of 9.1% from 2018 to 2025. Capsules are relatively stable shells that contain or encapsulate medicines, which are administered in a variety of dosage forms. Empty capsules are of two types in the market namely, gelatin capsules and non-gelatin capsules. Of these, the vegetable/non-gelatin capsules are expected to witness considerable demand in the coming years. This is attributed to the preference for the same among the consumers due to its natural or non-animal origin. The growth of the nutraceuticals industry has provided a shot in the arm to the global empty capsules market. Nutraceuticals have become popular across a range of demographics and regions due to their convenience in complementing a regular diet and help the individual maintain optimum health. The increasing adoption of unhealthy lifestyles by urban consumers across the world, particularly in developed regions, has led to growing demand for nutraceuticals, which is likely to remain a key driver for the global empty capsules market in the coming years. Apart from nutraceuticals, the branching out of the pharmaceuticals industry into the cosmeceuticals sector also has significant potential for the empty capsules market. The demand for capsules is growing on account of the mounting consumption of medicines worldwide. This trend augurs well for the global empty capsules market, where growth has thus far been driven by the demand for both nongelatin and hard gelatin capsules. The changing demographics of the world have necessitated the greater production of medicines to treat various kinds of diseases. Capsules, being among the most versatile forms of administering drug doses, are thus expected to be consumed in larger volumes over the next few years. The consumption demand for empty capsules is shaped by factors like health conditions of the aging population, clinical trial testing of formulations, changing consumer lifestyles, and edible beauty products with specific application in pharma, nutraceutical, and cosmetic industries. The key factors that boost the growth of the global empty capsules market include growth in popularity of capsules over other drug delivery forms and increase in strategic collaborations between empty capsule suppliers and gelatin manufacturers. In addition, rapid advancements in capsule delivery technologies are set to supplement the market growth. However, ethical concerns, price fluctuations regarding gelatin material, and stringent regulations in the pharmaceutical industry are expected to hamper the market growth. Nevertheless, soaring investments by pharmaceutical manufacturers in untapped economies offer profitable opportunities for the expansion of the market. The demand for empty capsules is expected to rise substantially in the years ahead thanks largely to the overall growth and expansion of the global pharmaceuticals industry. Moreover, the greater demand for nutraceuticals will also provide the global capsules market an opportunity to expand as several food supplements and functional foods are encapsulated to make them convenient for on-the-go consumption. The empty capsules market is dominated by top three players, namely, Capsugel (US), ACG Worldwide (India), and Qualicaps (Japan). Some of the other key players in this market are Suheung Co. Ltd. (Korea), CapsCanada Corporation (Canada), Qingdao Yiqing Medicinal Capsules Co., Ltd. (China), Shanxi Guangsheng Medicinal Capsules Co., Ltd (China), Healthcaps India Ltd. (India), Snail Pharma Industry Co. Ltd. (China), Roxlor (US), Sunil Healthcare Ltd. (India), Medi-Caps Ltd. (India), Nectar Lifesciences Ltd. (India), Natural Capsules Ltd. (India), and Bright Pharma Caps Inc. (US). Tags #Hard_Gelatin_Capsules, #Empty_Hard_Gelatin_Capsules, #Gelatin_Capsules, Manufacturing of Empty Hard Gelatin Capsules, #Empty_Hard_Gelatin_Capsules_Manufacture, Hard Gelatin Capsule Manufacturing Process Pdf, Preparation of Empty Gelatin Capsule, Empty Capsules, #Gelatin_Capsule_Manufacture, Capsule Manufacture, Capsule Manufacturing, Empty Gelatin Capsules, #Production_of_Empty_Hard_Gelatin, Manufacture of Hard Gelatin Capsules, Pharmaceutical Capsule Manufacture, Empty Capsules, Empty Gel Capsules, Gelatin Capsule Manufacturing Business, Gelatin Capsule Manufacturing, #How_to_Start_Empty_Gelatin_Capsule_Manufacturing_Business, Hard Gelatin Capsule Manufacturing Plant, Capsule Manufacture, Empty Gelatin Capsule Manufacturing Process, Capsule Production, Hard Gelatin Capsule Manufacturing Process, #Hard_Gelatin_Capsule_Manufacturing_Process_Pdf, Empty Hard Gelatin Capsules Production, Empty Capsule Production, Empty Capsule Making Business, How Empty Gelatin Capsules are Produced, Capsule Manufacturing Process Flow Chart, Manufacturing of Empty Gelatin Capsules, Project Report on Gelatin Capsule Manufacturing Industry, #Detailed_Project_Report_on_Empty_Hard_Gelatin_Capsules_Production, Project Report on Empty Hard Gelatin Capsules Production, Pre-Investment Feasibility Study on Empty Gelatin Capsule Manufacturing Business, Techno-Economic feasibility study on Empty Hard Gelatin Capsules Production, #Feasibility_report_on_Hard_Gelatin_Capsule_Manufacturing_Business, Free Project Profile on Hard Gelatin Capsule Manufacturing Industry, Project profile on Gelatin Capsule Manufacturing, Download free project profile on Empty Hard Gelatin Capsules Production
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Return: 1.00%Break even: N/A
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