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Pharmaceutical, Drugs, Fine Chemicals, Bulk Drug Intermediates, Pharmaceutical Drugs, Pharma Drug Ingredients Intermediates, Drug Intermediates, Speciality Chemicals, Raw Materials, Fine and Specialty Chemicals Intermediates, Pharmaceutical Bulk Drugs

Indian drugs and pharmaceutical industry has advanced perceptibly and is getting ready  for the new patent regime and  to withstand global competition, which is expected to be unleashed by new winds of liberalisation - a new era of liberalisation - much different from what was ushered in since the conclusion of the Uruguay Round and the establishment of the World Trade Organisation.

The industry has been expanding at annual rates ranging between 8 to 10% (against global growth rate of 6%).  According to a study  by McKinsey, Vision 2010, the domestic pharmaceutical industry could attain a size of  $25 billion (Rs 1200 billion) by 2010 by focusing on two areas: first, innovation-led research, development and new drug discoveries; and second, information technology-led remote sales and marketing.  The market for bulk drugs and formulations had increased from about Rs 103  billion in 1990-91 to an estimated Rs 435  billion at the end of 2003-04.  The prices of Indian essential drugs are among the lowest in the world. Apart from strides made by the industry in the last half-a-century, lower production cost due to reverse engineering and low R&D outlays has been a major factor in keeping the prices under check.

The global pharmaceutical industry is estimated at $ 300 billion, not all representing cross-border trade.  India's measly share of $ 1.5 billion in global trade represents an untapped potential. Under the regime of economic liberalisation underway since early 1990s, the drugs and pharmaceutical sector witnessed initiatives at fresh investment in the sector. Nearly 1735 investment proposals of the order of around Rs 166  billion were initiated. The foreign collaboration proposals approved numbered around 425 with a foreign direct investment  (FDI) component of over Rs 25 billion. The pharmaceuticals have figured high on the export front. In 2001-02,  the sector was  estimated to have registered a growth of 17.6% at around Rs 20.3 billion.

In the wake of economic liberalisation, many a  overseas players  returned or contemplated returning to India. These include Ivox Corp (USA),  Taro Pharmaceuticals (Israel) and Merck (USA). These are out either to set shop or looking for acquisitions in India. Hexal AG of Germany has established a liaison office in India. MILLIONCs like Rocha, Bayer, Aventis and Chiron are making India a regional hub for bulk drugs. 

The Export Import Bank of India (Exim Bank) had  doubled its corpus for the pharmaceutical industry to Rs 2 billion as a result of increased activity in the industry, especially in the external sector. The fund is used for the development and commercialisation of the new products and applications, significant improvement in the existing design of  products, setting up and expansion of pilot plants, research studies for obtaining regulatory approvals, cost of filing and managing international patent and R&D Centres.

It needs, however, to be recognised that the presence  of small scale manufacturers has resulted, on the one hand,  in a highly fragmented industry, and on the other, it has made it possible to supply a near 100,000 drugs including vitamins, antibiotics, antibacterials, cardio-vascular and other essential drugs. These account for nearly 37% of the market.  While each of about 80% of the manufacturers has annual sales below a billion rupees, top ten companies are known to control over 30% of the market. At present there are more than 20,000 players in the country.

The major players are: Alembic Chem, Aurobindo Pharma, Cipla, Dr. Reddy's, FDC, IPCA Labs, Jagsonpal Pharma, J.B. Chemicals, Kopran, Lupin Labs, Lyka Labs, Morepan Labs, Nicholas Piramal, Ranbaxy Labs, Sun Pharma, Themis Medicare, GlaxoSmithkline, Astrazeneca, Aventis, E-Merck, Torrent Pharma, TTK Healthcare, Unichem Labs,  Wockhardt  and  Zandu Pharma.  Until recently, only a few of the Indian companies had gone into any serious R&D activity. Much of the effort was directed to affordable analogue research. The R&D level in the country is low with even well-placed pharma companies spending less than 2% of turnover on R&D. MILLIONCs are known to contribute as much as 10% or more of their turnover to R&D.  While India is very strong in process chemistry, biology and applied bio-chemistry, initiatives at all levels - government, academia, private sector - involving heavy financial outlays, are called for.

Ayurveda continues to remain a preferred system of medicine for a vast segment of population in the country. The country has over 400,000 registered practitioners of the Indian system of medicine. Around 170 institutes properly affiliated to various universities impart under- or post-graduate courses each year. These institutes churn out some 5,500 fresh practitioners. The practitioners are supported by 12,000 dispensaries and 2,100 beds available for ayurveda treatment countrywide. The emerging biotechnology sector has already taken by storm and is offering sops to states to make these as the thriving ground for the highly potential segment in medicare.

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Invert Sugar Syrup

Invert sugar (syrup) is an edible mixture of sugars made by heating up table sugar (sucrose) with water. As invert sugar is thought to be sweeter than table sugar and foods that contain it hold in moisture and crystallize less easily, bakers, who call it invert syrup, may use it more than other sweeteners. Invert sugar (C12H24O12) is a mixture of glucose and fructose obtained by the hydrolysis of sucrose. Cane sugar comes from sugarcane. Invert Syrup contains equal proportions of the invert (reducing) sugars: glucose and fructose. It has wide application and is particularly useful where high concentrations of invert sugars are required. The requirement for invert sugar syrup has been on the rise in India. There is a gradual realization among both bakers and honey makers that it is almost impossible to achieve the same quality of invert sugar using in-house production. The global liquid sugar market is segmented based on type, application, and geography. The inverted sugar syrup segment is expected to grow at a faster rate comparatively due to its extensive application in non-alcoholic refreshing beverages. As a whole you can invest in this project without risk and earn profit. Few Indian major players are as under • Dhampure Specialty Sugars Ltd. • Eastern Sugar & Inds. Ltd. • Gem Sugars Ltd. • Sangita Bio-Chem Ltd. • U P Organics Ltd.
Plant capacity: Invert Sugar Syrup: 20 MT/DayPlant & machinery: Rs 397 lakhs
Working capital: -T.C.I: Cost of Project : Rs 733 lakhs
Return: 27.00%Break even: 58.00%
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Curcumin Extraction Unit

Curcumin is the main biologically active phytochemical compound of Turmeric. Molecular chemical formula of Curcumin: C21H20O6. The most important constituents in organic turmeric are Curcuminoids, which is approximately 6%, and the yellow coloring principles of which Curcumin constitutes 50-60%. Curcumin is a water-soluble orange-yellow coloured powder. Today, India is the primary exporter of turmeric (known as haldi in India). Curcumin is one of three curcuminoids of turmeric. The other two curcuminoids are demethoxycurcumin and bisdemethoxy curcumin. Curcumin production is mainly concentrated in India exceeding 78% of the global output. The industry expects the significant growth in China, India, Brazil, and South Africa. The BRIC nations will represent more than 44% of the global OTC demand by 2024. This facilitates the development of new technologies and ensures a high quality product. Few Indian major players are as under • Arjuna Natural Extracts Ltd. • Concert Spices & Exports Ltd. • Enjayes Spices & Chemical Oils Ltd. • Naturite Agro Products Ltd. • Sanat Products Ltd. • Synthite Industries Ltd.
Plant capacity: Curcumin Powder: 25 Kgs/Day Turmeric Oil : 25 Kgs/Day Deoiled Turmeric : 440 Kgs/DayPlant & machinery: Rs 149 lakhs
Working capital: -T.C.I: Cost of Project: Rs 303 lakhs
Return: 26.00%Break even: 52.00%
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Homeo & Bio Medicines with Mother Tincture

Homeopathy is a type of option drug made in 1796 by Samuel Hahnemann taking into account his regulation of like cures like (similia similibus curentur), whereby a substance that causes the side effects of a sickness in solid individuals will cure comparable manifestations in wiped out individuals. Biomedicine is a major engine for both medical progress and economic growth as well as an integral part of how health, illness, and individual identity are understood. However, the foundations of biomedicine are in the midst of a great transformation, a transformation with profound implications for medicine, research, commerce, and public policy. Global homeopathy product market will exhibit a promising 18.2% CAGR over the period between 2016 and 2024. If the number holds true, the market, which valued at US$3,867.7 mn in 2015, is expected to reach US$17,486.2 mn by 2024.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Bulk Drugs

A bulk drug also called active pharmaceutical ingredient (API) is the chemical molecule in a pharmaceutical product (medicines we buy from the chemist) that lends the product the claimed therapeutic effect. In other words, it is the substance responsible for the product being a medicine, penicillin to give one example. As is evident from this, there are ingredients other than the API in products sold as medicines. After years of sluggish growth, Indian bulk drug (API, Active Pharmaceutical Ingredients) industry is expected to recover in 2018-19, driven by solid demand from the formulation industry and strong growth in direct exports on the back of low intermediate chemical prices supported by low crude oil prices. The country’s bulk drug market is 3rd largest in the world in terms of volume and 13th largest in terms of value. India’s bulk drug production has seen a stable growth in the last couple of years in the generic sector and is expected to grow at a healthy CAGR of 7.5% in the forecast period 2017-2022. The global Active Pharmaceutical Ingredient (API) market size was valued at USD 134.2 billion in the year 2015 and is estimated to reach a value of USD 239.8 billion by 2025, growing with CAGR of 6.0 %. The market growth can be linked to the rising prevalence of chronic diseases such as cancer, neurological diseases, and cardiovascular diseases. Increasing demand for rapid-acting & efficient drugs and introduction of innovative drug manufacturing facilities are other key drivers estimated to fuel growth of this market over the forecast period.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Dextrose 5%

Dextrose is the name of a simple sugar that is made from corn and is chemically identical to glucose, or blood sugar. Dextrose is often used in baking products as a sweetener, and can be commonly found in items such as processed foods and corn syrup. Dextrose also has medical purposes. It is dissolved in solutions that are given intravenously, which can be combined with other drugs, or used to increase a person’s blood sugar. Because dextrose is a “simple” sugar, the body can quickly use it for energy. Dextrose is a form of glucose derived from starches. It is one of the most commonly used ingredients in packaged foods because of its affordability and wide availability. Baking products and desserts often contain dextrose, but it may be used as an added sugar in any processed food that is sweetened by the manufacturer. Because the name varies depending on its original starch source, you may not realize a particular food contains dextrose. Dextrose 5% in water is sometimes used as a diluent (liquid) for preparing injectable medication in an IV bag. A diluent provides a large amount of fluid in which to dilute a small amount of medicine. The diluent helps carry the medicine into your bloodstream through the IV. This helps your caregivers inject the medicine slowly and more safely into your body. Global glucose (dextrose) market is expected to witness a rapid increase in demand due to the rise in consumption of glucose syrup over the forecast period. Glucose syrup accounts for a majority share in the global starch derivatives market owing to its wide range use in the manufacture of candy products and is poised to grow at a very intense rate by the end of 2020. Some other derivatives of glucose include maltodextrin, hydolysates and cyclodextrin. Glucose is primarily used along with sugar as it exhibits complimentary characteristics to natural sugar such as preventing sugar from crystallizing, reducing stickiness of sugar and retention of extra moisture. Glucose is extensively used as an additive in pharmaceuticals and nutrition foods owing to its high energy content. Over the past few years, there has been an increasing use of glucose in the form of tablets or medicine for patients having low blood sugar. Growth of the pharmaceutical industry is expected to augment demand for glucose over the forecast period.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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IV Fluids (BFS Technology)

Intravenous fluids are fluids which are intended to be administered to a patient intravenously, directly through the circulatory system. These fluids must be sterile to protect patients from injury, and there are a number of different types available for use. Intravenous fluids can also be used as a route of medication administration. If a doctor wants to deliver a small amount of medication over an extended period of time, it can be dissolved in a bag of intravenous fluids and set on an infusion pump which delivers the medicated fluid directly into the blood. The Indian pharmaceutical industry is the fourth largest in the world in terms of volume of output and thirteenth in domestic demand. However, the Indian industry, valued at USD 17 bn in represented just over 1% of the global pharmaceutical industry (USD 1700 bn) in value terms. The domestic market is estimated at Rs 680 bn. Intravenous (IV) fluids market in India is around Rs. 3,000 crore growing at healthy rate of around 15-20 per cent a year due to its essential requirement in nature. Entrepreneurs who invest in this project will be successful. Few Indian major players are as under • Abaris Healthcare Pvt. Ltd. • AhlconParenterals (India) Ltd. • AxaParenterals Ltd. • Infutec Healthcare Ltd. • Kokad Pharmaceutical Laboratories Ltd. • Parenteral Surgicals Ltd.
Plant capacity: IV Fluids (500 ml Bottle): 49600 Pcs./DayPlant & machinery: Rs. 1954 lakhs
Working capital: -T.C.I: Cost of Project: Rs. 2756 lakhs
Return: 25.00%Break even: 52.00%
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Disposable Plastic Syringes

Disposable Syringes are made of plastic material and are used in the field of medical and veterinary science. Due to their availability in sterilized condition, ready to use, and cost effectiveness, disposable syringes are fast replacing the age-old glass syringes. Disposable Syringes are being used by doctors to inject medicines through intravenous or intramuscular ways for the treatment of diseases & also by research & development personnel. The effective result of the above factors of influence on the market – along with a few others – for disposable syringes is expected to translate to a CAGR of 5.6% from 2015 to 2023.India is witnessing a rapid growth across all segments and categories of medical products. India exported US$ 35.22 million worth of syringes and the overall exported quantity was 719.48 million units. Thus, due to demand it is best to invest in this project. Few Indian major players are as under • Albert David Ltd. • Disposable Medi-Aids Ltd. • Hindustan Syringes & Medical Devices Ltd. • Lifeline Injects Ltd. • Lifelong Meditech Ltd. • Oyster Medisafe Pvt. Ltd.
Plant capacity: Disposable Plastic Syringes: 460 Boxes/DayPlant & machinery: Rs. 115 lakhs
Working capital: -T.C.I: Cost of Project: Rs. 289 lakhs
Return: 18.00%Break even: 67.00%
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Cow Urine (Gomutra)Processing and Packing

Gomutra is not a toxic waste material. 95% of it is water, 2.5% consists of urea, and the remaining 2.5% is a mixture of minerals, salts, hormones and enzymes.Gomutra or gaumutra cow urine is urine from cows used for therapeutic purposes in traditional Indian medicine, Ayurveda and also for purification in VaastuShastra.Cow urine has bio enhancing activity for Rifampicin, the front-line anti-tubercular drug used against tuberculosis, increasing its action up to sevenfold against Escherichia coli, and up to 11-fold against Gram-positive bacteria. There are more than 50 units processing cow urine in India. That cow urine is in demand not just in India, but around the world, became evident recently when health authorities in London raised objections to shopkeepers placing cow urine concentrate on shelves next to food items.As a whole any entrepreneur can venture in this project without risk and earn profit.
Plant capacity: Distilled Cow Urine (Gomutra): 2000Lts./DayPlant & machinery: Rs.22 lakhs
Working capital: -T.C.I: Cost of Project: Rs.187 lakhs
Return: 28.00%Break even: 68.00%
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Soft Gelatin Capsules

Soft gelatin (also called softgel or soft elastic) capsules consist of one piece hermetically-sealed soft shells. Soft gelatin capsules are prepared by adding a plasticizer, such as glycerin or polyhydric alcohol (e.g., sorbitol), to gelatin. The plasticizer makes gelatin elastic. Soft gelatin capsules come in various shapes such as spherical, elliptical, oblong, and special tube shapes with and without twist off. The demand of the soft gel capsules is increasing due to the available customization facilities for the molds and content as per customer needs.The Global Softgel Capsules Market is poised to grow at a CAGR of around 5.4% over the next decade to reach approximately $316.6 billion by 2025.Which facilitates the development of new technologies and ensure a high quality product. Few Indian major players are as under • C J Gelatine Products Ltd. • Fortcaps Healthcare Ltd. • Healthcaps India Ltd. • India Gelatine& Chemicals Ltd. • K P Gelatines& Chemicals India Ltd. • MarksansPharma Ltd. • Medgel Pvt. Ltd.
Plant capacity: Soft Gelatin Capsules: 3120000Nos./DayPlant & machinery: Rs. 649 lakhs
Working capital: -T.C.I: Cost of Project: Rs. 10871 lakhs
Return: 35.00%Break even: 31.00%
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Caffeine from Tea Waste

Caffeine belongs to a family of naturally occurring compounds known as xanthines. The xanthines, which come from plants, are possibly the oldest known stimulants. Caffeine is widely used in pharmaceuticals as free base and mixtures, such as 'Citrated Caffeine’s caffeine and sodium benzoate. Caffeine is very much used as a stimulant of the central nervous system and also as a diuretic, although its action as a diuretic is weaker than that of the ophyline. There is about 10% demand growth increase per annum. Up to 400 milligrams (mg) of caffeine a day appears to be safe for most healthy adults. That's roughly the amount of caffeine in four cups of brewed coffee, 10 cans of cola or two "energy shot" drinks.The global caffeine market is predicted to expand at a steady CAGR of around 2.5% by 2022.Entrepreneurs who invest in this project will be successful. Few Indian major players are as under • Aarti Drugs Ltd. • Aarti Industries Ltd. • Ankur Drugs &Pharma Ltd. • AstecLifesciences Ltd. • Bajaj Healthcare Ltd. • Bengal Chemicals & Pharmaceuticals Ltd.
Plant capacity: Caffeine: 20 MT/dayPlant & machinery: Rs. 350 lakhs
Working capital: -T.C.I: Cost of Project: Rs. 2268 lakhs
Return: 30.00%Break even: 61.00%
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Information
  • One Lac / Lakh / Lakhs is equivalent to one hundred thousand (100,000)
  • One Crore is equivalent to ten million (10,000,000)
  • T.C.I is Total Capital Investment
  • We can modify the project capacity and project cost as per your requirement.
  • We can also prepare project report on any subject as per your requirement.
  • Caution: The project's cost, capacity and return are subject to change without any notice. Future projects may have different values of project cost, capacity or return.

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