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Pharmaceutical, Drugs, Fine Chemicals, Bulk Drug Intermediates, Pharmaceutical Drugs, Pharma Drug Ingredients Intermediates, Drug Intermediates, Speciality Chemicals, Raw Materials, Fine and Specialty Chemicals Intermediates, Pharmaceutical Bulk Drugs

Indian drugs and pharmaceutical industry has advanced perceptibly and is getting ready  for the new patent regime and  to withstand global competition, which is expected to be unleashed by new winds of liberalisation - a new era of liberalisation - much different from what was ushered in since the conclusion of the Uruguay Round and the establishment of the World Trade Organisation.

The industry has been expanding at annual rates ranging between 8 to 10% (against global growth rate of 6%).  According to a study  by McKinsey, Vision 2010, the domestic pharmaceutical industry could attain a size of  $25 billion (Rs 1200 billion) by 2010 by focusing on two areas: first, innovation-led research, development and new drug discoveries; and second, information technology-led remote sales and marketing.  The market for bulk drugs and formulations had increased from about Rs 103  billion in 1990-91 to an estimated Rs 435  billion at the end of 2003-04.  The prices of Indian essential drugs are among the lowest in the world. Apart from strides made by the industry in the last half-a-century, lower production cost due to reverse engineering and low R&D outlays has been a major factor in keeping the prices under check.

The global pharmaceutical industry is estimated at $ 300 billion, not all representing cross-border trade.  India's measly share of $ 1.5 billion in global trade represents an untapped potential. Under the regime of economic liberalisation underway since early 1990s, the drugs and pharmaceutical sector witnessed initiatives at fresh investment in the sector. Nearly 1735 investment proposals of the order of around Rs 166  billion were initiated. The foreign collaboration proposals approved numbered around 425 with a foreign direct investment  (FDI) component of over Rs 25 billion. The pharmaceuticals have figured high on the export front. In 2001-02,  the sector was  estimated to have registered a growth of 17.6% at around Rs 20.3 billion.

In the wake of economic liberalisation, many a  overseas players  returned or contemplated returning to India. These include Ivox Corp (USA),  Taro Pharmaceuticals (Israel) and Merck (USA). These are out either to set shop or looking for acquisitions in India. Hexal AG of Germany has established a liaison office in India. MILLIONCs like Rocha, Bayer, Aventis and Chiron are making India a regional hub for bulk drugs. 

The Export Import Bank of India (Exim Bank) had  doubled its corpus for the pharmaceutical industry to Rs 2 billion as a result of increased activity in the industry, especially in the external sector. The fund is used for the development and commercialisation of the new products and applications, significant improvement in the existing design of  products, setting up and expansion of pilot plants, research studies for obtaining regulatory approvals, cost of filing and managing international patent and R&D Centres.

It needs, however, to be recognised that the presence  of small scale manufacturers has resulted, on the one hand,  in a highly fragmented industry, and on the other, it has made it possible to supply a near 100,000 drugs including vitamins, antibiotics, antibacterials, cardio-vascular and other essential drugs. These account for nearly 37% of the market.  While each of about 80% of the manufacturers has annual sales below a billion rupees, top ten companies are known to control over 30% of the market. At present there are more than 20,000 players in the country.

The major players are: Alembic Chem, Aurobindo Pharma, Cipla, Dr. Reddy's, FDC, IPCA Labs, Jagsonpal Pharma, J.B. Chemicals, Kopran, Lupin Labs, Lyka Labs, Morepan Labs, Nicholas Piramal, Ranbaxy Labs, Sun Pharma, Themis Medicare, GlaxoSmithkline, Astrazeneca, Aventis, E-Merck, Torrent Pharma, TTK Healthcare, Unichem Labs,  Wockhardt  and  Zandu Pharma.  Until recently, only a few of the Indian companies had gone into any serious R&D activity. Much of the effort was directed to affordable analogue research. The R&D level in the country is low with even well-placed pharma companies spending less than 2% of turnover on R&D. MILLIONCs are known to contribute as much as 10% or more of their turnover to R&D.  While India is very strong in process chemistry, biology and applied bio-chemistry, initiatives at all levels - government, academia, private sector - involving heavy financial outlays, are called for.

Ayurveda continues to remain a preferred system of medicine for a vast segment of population in the country. The country has over 400,000 registered practitioners of the Indian system of medicine. Around 170 institutes properly affiliated to various universities impart under- or post-graduate courses each year. These institutes churn out some 5,500 fresh practitioners. The practitioners are supported by 12,000 dispensaries and 2,100 beds available for ayurveda treatment countrywide. The emerging biotechnology sector has already taken by storm and is offering sops to states to make these as the thriving ground for the highly potential segment in medicare.

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IV (intravenous) Fluids [Form Fill Seal (FFS) Technology] - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Plant Layout

Intravenous fluids are fluids which are intended to be administered to a patient intravenously, directly through the circulatory system. These fluids must be sterile to protect patients from injury, and there are a number of different types available for use. Many companies manufacture packaged intravenous fluids, as well as products which can be mixed with sterile water to prepare a solution for intravenous administration. Fluids are given when someones body fluid volume falls. There are a number of things which can cause a drop in fluid volume. Vomiting and diarrhea are a classic example, which is why people are encouraged to drink fluids when they are sick, to keep their fluid volume stable. Another cause is blood loss, which causes problems both because people lose blood products, and because they experience a loss in fluid volume. Electrolyte levels in the blood can also become unstable as a result of rapid changes in fluid volume, in which case intravenous fluids can be used to restore the balance. Uses and Application There are four main ranges of application of highly specialized intravenous infusion solutions: Aqueous isotonic injection (5%) of dextrose is given as intravenous injections to increase the column of circulating blood in the shocks and haemarrhages and to counteract dehydration. When it is desired to replace excessive salt loss also glucose is injected along with sodium chloride, Dextrose solution is used during postoperative period when sodium extraction is reduced, Dextrose solution with concentration of 10 to 15% are used as diuretic for increase in urine flow, Dextrose solution of 5% normal salinic are used for restoring fluid volume in circulation of an emergency as in accidents with haemarrhage. Market Survey Indias traditions in the science of health and healing go back to the halcyon days of Surushta, Vagbhatta and Charaka. Our system of medicine like Ayurveda was well established and schools and hospitals with treatises and instruction manuals were in wide use. I.V. fluid demand is normally linked to the number of hospital beds. Observations show that 18 bottles of I.V. fluids are consumed per bed per month in the country. The demand is estimated to increase at a rate of 9 to 12% per annum. The growth of I.V fluid manufacturing was faster than the growth rate of drugs. I.V fluids are the solutions applied directly to the vein of a patient who suffer from the weaknesses due to the deficiency of body fluids. These I.V. fluids are the best alternative, which can yield sudden result in the health of a patient by replenishing the body fluids.
Plant capacity: 9000000 Nos. Bottles/ Annum(Each 1000 ml. Bottles)Plant & machinery: 851 Lakhs
Working capital: -T.C.I: Cost of Project : 1251 Lakhs
Return: 43.00%Break even: 49.00%
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DISPOSABLE PLASTIC SYRINGES - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

A syringe is a simple piston pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube (the barrel), allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle, or tubing to help direct the flow into and out of the barrel. The disposable plastic syringe has become an important part of the medical scene since its introduction in the late 1950's. Today more and more attention is being focused on the composition and configuration of this everyday item. It is an instrument which is used for injecting any liquid into the body of human beings or of animals. These syringes are used for injecting the medicine into the body or into the nerve of the body which are not possible to take in through mouth or takes much time in mixing with blood. Disposable Syringes made of plastic Material have been successfully used in medical and pharmaceutical practice for many years. The constantly increasing use of this type Syringe indicates its importance, which is based mainly on the advantages it offers regarding cost and hygienic applications. Plastic syringes are becoming more popular in the medical world due to its lower cost and higher accuracy. Uses & Applications Disposable syringes commonly are used in modern medicine for the injection of drugs and vaccines or for the extraction of blood. The often are used instead of reusable syringes in an effort to avoid spreading a disease. Among the common uses of disposable syringes are the injecting of insulin by a diabetic person and the administering of a local anesthesia by a dentist. A medical syringe that is used to give shots to more than one person without being properly sterilized is a potential source of disease. This can be an especially pressing concern in poor or undeveloped areas, where an injection often cannot be given under ideal medical conditions. Therefore, disposable syringes often are favored over reusable syringes for vaccines, in order to avoid the risk of transmitting blood borne diseases such as human immunodeficiency virus (HIV) and hepatitis from one person to another. Needle exchange programs that provide intravenous drug users with disposable syringes and needles are based on the same idea, because reuse and sharing of infected needles by drug users is one of the principal ways HIV is transmitted in the developed world. Market Survey Needles and syringes are amongst the most extensively used medical disposables. Healthcare professionals represent the largest end use market for syringes, followed by diabetics. A substantial rise in the number of drug addicts has also contributed to the enhanced demand for syringes across the world. Rising life expectancies and growing proportion of the elderly have led to increased demand for healthcare services, and greater need for drugs to be injected. Additionally, a number of newly introduced drugs including DNA based drugs are not available in the form of pills and must be administered intravenously, thereby enhancing the demand for disposable syringes. Worldwide market for syringes is driven by an aging population and related rise in healthcare demand. The Present demand of Disposable syringes is being adequately met by indigenous production. In increasing awareness in health care, AIDs and like diseases and improvement in per capita income is expected to create further growth in demand of disposable syringe / needles. Since there is in need to add few more new units for manufacturing of Disposable Syringe. The growth in domestic demand may be conservatively expected to be 25% per annum, assuming constant export of 100 million syringes /year only. One additional unit every year with 25 million products shall be needed to increase in indigenous demand alone besides increase in export quantities is likely to be the further aggravate the demand. The Industry is exporting about 80 million syringes annually which is reasonably spread amongst various units. The measure importing country is Russia. (For sustained exports on durable basis, accreditation under ISO: 14000 or ISP 9000 is mandatory. Imports are limited to certain sizes like 10.20 and 50 ml because of relatively uneconomical demand quantities in such sizes. The total imported in all size may be 35 40 million pieces. Few Indian Major Players are as Under: Albert David Ltd. Disposable Medi Aids Ltd. H L L Lifecare Ltd. Hindustan Syringes & Medical Devices Ltd. Iscon Surgicals Ltd. La Medical Devices Ltd. Lifeline Injects Ltd. Lifelong Meditech Ltd. Nirma Ltd. Raaj Medisafe India Ltd. Sangam Health Care Products Ltd. Surgiplast Ltd.
Plant capacity: 16800 Nos. Syringes (2.5 ml size/day),16800 Nos. Syringes/ (5 ml size/day)Plant & machinery: 104 Lakhs
Working capital: -T.C.I: Cost of Project : 255 Lakhs
Return: 26.00%Break even: 48.00%
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DISPOSABLE PLASTIC SYRINGES - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

A syringe is a simple piston pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube (the barrel), allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle, or tubing to help direct the flow into and out of the barrel. The disposable plastic syringe has become an important part of the medical scene since its introduction in the late 1950's. Today more and more attention is being focused on the composition and configuration of this everyday item. It is an instrument which is used for injecting any liquid into the body of human beings or of animals. These syringes are used for injecting the medicine into the body or into the nerve of the body which are not possible to take in through mouth or takes much time in mixing with blood. Disposable Syringes made of plastic Material have been successfully used in medical and pharmaceutical practice for many years. The constantly increasing use of this type Syringe indicates its importance, which is based mainly on the advantages it offers regarding cost and hygienic applications. Plastic syringes are becoming more popular in the medical world due to its lower cost and higher accuracy. Uses & Applications Disposable syringes commonly are used in modern medicine for the injection of drugs and vaccines or for the extraction of blood. The often are used instead of reusable syringes in an effort to avoid spreading a disease. Among the common uses of disposable syringes are the injecting of insulin by a diabetic person and the administering of a local anesthesia by a dentist. A medical syringe that is used to give shots to more than one person without being properly sterilized is a potential source of disease. This can be an especially pressing concern in poor or undeveloped areas, where an injection often cannot be given under ideal medical conditions. Therefore, disposable syringes often are favored over reusable syringes for vaccines, in order to avoid the risk of transmitting blood borne diseases such as human immunodeficiency virus (HIV) and hepatitis from one person to another. Needle exchange programs that provide intravenous drug users with disposable syringes and needles are based on the same idea, because reuse and sharing of infected needles by drug users is one of the principal ways HIV is transmitted in the developed world. Market Survey Needles and syringes are amongst the most extensively used medical disposables. Healthcare professionals represent the largest end use market for syringes, followed by diabetics. A substantial rise in the number of drug addicts has also contributed to the enhanced demand for syringes across the world. Rising life expectancies and growing proportion of the elderly have led to increased demand for healthcare services, and greater need for drugs to be injected. Additionally, a number of newly introduced drugs including DNA based drugs are not available in the form of pills and must be administered intravenously, thereby enhancing the demand for disposable syringes. Worldwide market for syringes is driven by an aging population and related rise in healthcare demand. The Present demand of Disposable syringes is being adequately met by indigenous production. In increasing awareness in health care, AIDs and like diseases and improvement in per capita income is expected to create further growth in demand of disposable syringe / needles. Since there is in need to add few more new units for manufacturing of Disposable Syringe. The growth in domestic demand may be conservatively expected to be 25% per annum, assuming constant export of 100 million syringes /year only. One additional unit every year with 25 million products shall be needed to increase in indigenous demand alone besides increase in export quantities is likely to be the further aggravate the demand. The Industry is exporting about 80 million syringes annually which is reasonably spread amongst various units. The measure importing country is Russia. (For sustained exports on durable basis, accreditation under ISO: 14000 or ISP 9000 is mandatory. Imports are limited to certain sizes like 10.20 and 50 ml because of relatively uneconomical demand quantities in such sizes. The total imported in all size may be 35 40 million pieces. Few Indian Major Players are as Under: Albert David Ltd. Disposable Medi Aids Ltd. H L L Lifecare Ltd. Hindustan Syringes & Medical Devices Ltd. Iscon Surgicals Ltd. La Medical Devices Ltd. Lifeline Injects Ltd. Lifelong Meditech Ltd. Nirma Ltd. Raaj Medisafe India Ltd. Sangam Health Care Products Ltd. Surgiplast Ltd.
Plant capacity: 16800 Nos. Syringes (2.5 ml size/day),16800 Nos. Syringes/ (5 ml size/day)Plant & machinery: 104 Lakhs
Working capital: -T.C.I: Cost of Project : 255 Lakhs
Return: 26.00%Break even: 48.00%
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SOFT AND HARD GELATIN CAPSULES (VEGETABLE AND NON VEG. BASE)

A capsule is a shell or a container prepared from gelatin containing one or more medicinal and/or inert substances. The gelatin capsule shell may be soft or hard depending on their formulation. The term capsule derived from the Latin Capsula meaning small box. In 1833, Mothes first introduced the soft capsule (soft gel), which then in 1838 the invention is patentable. Hard Gelatin itself is discovered by Lehuby in 1846. Capsule can be used for internal usage (orally, through the nose, through the body cavity) and external usage (outside of the body). Capsule is a solid particle which has a size of 0.1 to 10,000 ?. According to the pharmacopoeia of Indonesia, the capsule is a solid dosage of the drug in hard or soft shell that can be dissolved. Shells are generally made of gelatin, can also be made from starch or other suitable material. Gelatin is defined as a product obtained by the partial hydrolysis of collagen derived from the skin white connective tissue and bones of animals. Gelatin derived from an acid treated pre curser is known as type A and gelatin derived from an alkali treated precursor is known as type B. Gelatin is a protein and in aqueous solution forms a hydrophilic colloid, leading to complex behavior. As a normal constituent of plant and animal tissues, it is essential to their growth. It occurs especially in seeds, the yolk of eggs, the nerves and brain and bone narrow, usually in the form of lecithins or glycero phosphates. It is an essential constituent of bones in the format calcium phosphate. Bone contains about 58% calcium phosphate plus some calcium carbonate, fat and nitrogenous organic matter. Technical gelatin generally refers to the gelatin that is used for non edible purposes. Uses & Applications The industry recognizes four different kinds of gelatin, edible, technical, photographic and pharmaceutical. Gelatin is widely consumed food, and it is popular dessert which is easily assimilated and even helps in the digestion of other foods by forming an emulsion with fats and proteins. Gelatin has played an important part in the rapid development of the motion picture and photographic industry. It is coated on the film base, constituting the sensitized emulsion of the light sensitive silver salts. Technical gelatin is quite an arbitrary name applied to small amounts used for miscellaneous purposes, such as for sizing paper, textiles and straw hats. Gelatin is used by pharmaceutical houses for making capsules and as an emulsifier. Advantages of Hard and Soft Gelatin Capsule Hard: Rapid drug release possible, Flexibility of formulation, Sealed HGCs are good barriers to atmospheric oxygen. Soft : High Accuracy/precision possible, Hermetically sealed (inherently), Possible bioavailability advantages, Reduced dustiness; lack of compression stage in manufacture, Possible reduced gastric irritancy compared to tablets and hard shell capsules, Specialty packages available. Market Survey Today Gelatin is a vital ingredient in the most popular drug delivery systems in the world such as two piece hard capsules, soft capsules, tablets, coated tablets, mini, micro capsules etc. The global gelatine market is set to continue its rise with gelatine consumption forecast to reach 395.84 thousand metric tons by 2017. Continued growth in the gelatine market is being fuelled by an aging population, focus on healthcare and increasing demand from end use industries such as food & beverage, nutraceuticals and pharmaceuticals. US based global industry Analysts( GIA) said the global gelatin market is growing fast the farm estimates that it will reach 357800 metric tons by 2015 driven by increasing demand for gelatin as bio material in cosmetics and from developing countries. Few Indian Major Players are as Under: A B L Biotechnologies Ltd. A C G Arts & Properties Pvt. Ltd. Capsugel Healthcare Ltd. Chemcaps Ltd. Dinesh Remedies Ltd. Healthcaps India Ltd. Medi Caps Ltd. Natural Capsules Ltd. Sunil Healthcare Ltd.
Plant capacity: 2880000 Nos. /dayPlant & machinery: 397 Lakhs
Working capital: -T.C.I: 637 Lakhs
Return: 36.00%Break even: 43.00%
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Surgical Cotton - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Layout

Surgical cotton is also known as absorbent cotton or cotton wool. It is mainly used for medical purposes in hospitals, nursing homes, and dispensaries & at home (for first aid) etc. because of its high fluid absorbency. It is better known among masses as absorbent cotton. Absorbent cotton consists of non woven fleeces of fire, roughly parallel, knot free cotton fibers, up to 30 mm in length to less than 20 mm. It is sterile & is therefore suitable for use in dressings. The raw cotton is processed by series of steps, which render the cotton hydrophilic in character & free from external impurities needed to be fit for use in surgical dressings & personal hygiene. It is almost plain cellulose and constitutes one of the basic raw materials of the various cellulose industries, including plastics, rayon & explosives. Uses and Applications Absorbent cotton or surgical cotton is used at each level from medical to corporate, and also individual’s level. This item is regulated under the Drugs Control Act. Hence, it should be manufactured to meet its requirements for quality control standard. Apart from used as a dressing material, it is also used for padding for items of clothing, quilts etc. Market Survey The report is an analysis of the 2007 nonwovens industry of India with an outlook to 2012. The nonwovens information is a compilation of data provided by major industry roll goods producers in India, government sources, consultants and various companies involved in the emerging Indian nonwovens industry. The report analyses the current consumption of nonwovens and related nonwoven products, either produced domestically or imported. A forecast through 2012 is provided for the significant nonwoven markets and discusses important trends that are driving consumption. The larger nonwoven disposables markets are covered, which include absorbent hygiene, premoistened baby wipes and medical; and durables: interlining, automotive, home furnishings and bedding, agricultural crop covers, roofing components, needle punched carpeting, geotextiles and coated/laminated substrates. The Indian markets consumed 11,100 tonnes in 2007, and we forecast these volumes will more than double to 23,200 tonnes during the five year forecast through 2012. The significant markets that will drive spun bonded polypropylene growth will be cover stock consumed by absorbent hygiene production, bedding and upholstered furnishings, agriculture and some medical end uses.
Plant capacity: 500 Kgs./DayPlant & machinery: 61 Lakhs
Working capital: -T.C.I: Cost of Project : 156 Lakhs
Return: 28.00%Break even: 52.00%
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Disposable Plastic Syringes - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

A syringe is a simple piston pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle, or tubing to help direct the flow into and out of the barrel. The disposable plastic syringe has become an important part of the medical scene since its introduction in the late 1950's. Today more and more attention is being focused on the composition and configuration of this everyday item. It is an instrument which is used for injecting any liquid into the body of human beings or of animals. These syringes are used for injecting the medicine into the body or into the nerve of the body which are not possible to take in through mouth or takes much time in mixing with blood. Disposable Syringes made of plastic Material have been successfully used in medical and pharmaceutical practice for many years. The constantly increasing use of this type Syringe indicates its importance, which is based mainly on the advantages it offers regarding cost and hygienic applications. Uses & Applications Disposable syringes commonly are used in modern medicine for the injection of drugs and vaccines or for the extraction of blood. The often are used instead of reusable syringes in an effort to avoid spreading a disease. Among the common uses of disposable syringes are the injecting of insulin by a diabetic person and the administering of a local anesthesia by a dentist .A medical syringe that is used to give shots to more than one person without being properly sterilized is a potential source of disease. This can be an especially pressing concern in poor or undeveloped areas, where an injection often cannot be given under ideal medical conditions. Market Survey The Health Ministry of the Government of India was planning to have a separate wing to license medical devices under the proposed National Drug Authority. The Indian domestic Medicare devices industry is expected to grow from Rs 60 bn to Rs 76.5 bn in four years. The overall market is estimated at Rs 150 bn. A major part of the demand is met through imports. Devices, such as catheters and stents represent nearly two fifth of the entire range of diagnostic devices and most critical as per international classification. The Government has decided to create separate quality guidelines for medical devices. Presently medical devices are treated like drugs and regulated by state drug regulators under the drug law Drugs and Cosmetics Act. Guidelines would make it mandatory for producers to get their products certified by notified bodies like ISO and BIS. Technological advances achieved by Medicare globally in the recent years have been phenomenal. The Indian scenario has not remained immune to these changes. While IT (information technology) has come to the aid of the breakthroughs, the progress recorded in the Medicare area is as impressive as it is in the IT sector itself. The changes are in concepts, forms and content, as well as applications. These are both, quantitative and qualitative. The transformation is pervasive and has penetrated almost all specialties, from diagnostics to physiotherapy, from cardiology to oncology, from non invasive surgery to transplants. Financial Analysis & Comparison of Major Companies Albert David Ltd. Disposable Medi Aids Ltd. H L L Lifecare Ltd. Hindustan Syringes & Medical Devices Ltd. Iscon Surgicals Ltd. La Medical Devices Ltd. Lifeline Injects Ltd. Lifelong Meditech Ltd. Nirma Ltd. Raaj Medisafe India Ltd. Sangam Health Care Products Ltd. Surgiplast Ltd.
Plant capacity: 33600 NOS./DayPlant & machinery: 112 Lakhs
Working capital: -T.C.I: Cost of Project : 287 Lakhs
Return: 30.00%Break even: 44.00%
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Salicylic acid/Aspirin - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Salicylic acid is an organic acid that has a colorless crystalline structure and is poorly soluble in water. Salicylic acid is a beta-hydroxy acid, which is a larger molecule than alpha-hydroxy acids and is widely used in topical formulations as a comedolytic and keratolytic agent. Beta-hydroxy acids are derived from plant hormones and are lipid soluble. Salicylic acid, or 2-hydroxybenzoic acid, is extracted from the bark of the willow tree, and systemic formulations provide pain relief and anti-inflammatory effects. Salicylic acid applied topically penetrates pores which contain sebum, thereby softening and removing the epithelium. Its larger molecular size limits penetration through the dermis to general circulation. Salicylic acid has been combined effectively with other ingredients for various topical applications. Salicylic acid is reacted with acetic anhydride to produce acetyl salicylic acid .Salicylic acid is used in the pharmaceutical sector as an antiseptic, disinfectant and anti-fungal agent. It is applied externally as a dusting powder, lotion or ointment for the treatment of dandruff, eczema, psoriasis and parasitic skin diseases. To destroy warts or crone, it is applied in a collusion or as a plaster. Salicylic acid has been shown to be effective in dermatologic and cosmetic applications for its rapid effect as a keratolytic agent. Products containing salicylic acid include facial cleansers and antidandruff shampoos. Salicylic acid has been added in trace amounts as a food preservative and in mild antiseptics, such as mouthwashes and toothpastes. Salicylic compounds have also been synthesized for analgesics and antipyretics . Aspirin is the most widely used over-the-counter drug in the world. The average tablet contains about 325 milligrams of acetylsalicylic acid with an inert binding material such as starch. Aspirin is used to relieve pain, reduce inflammation, and lower fever. Aspirin originally was derived by boiling the bark of the white willow tree. Although the salicylic in willow bark has analgesic properties, purified salicylic acid was bitter and irritating when taken orally. Salicylic acid was neutralized with sodium to produce sodium salicylate, which was better-tasting but still irritated the stomach. Salicylic acid could be modified to produce phenylsalicylate, which was better tasting and less irritating, but released the toxic substance phenol when metabolized. Demand trend of most salicylic acid is used as raw material for producing aspirin and a small amount of salicylic acid is sold as chemical raw material. So, the demand of salicylic acid is closely related to the output of aspirin. Manufacturing process of salicylic acid include three reaction steps involved in producing salicylic acid from the starting material namely phenol. First, sodium phenolate is prepared by reacting phenol and aqueous sodium hydroxide. The resulting solution is heated and evaporated to dryness. Second, a direct solid gas reaction between sodium phenolate and carbon dioxide is performed, producing sodium salicylate. Third, the sodium salicylate is dissolved in water and converted to salicylic acid by acidification with sulphuric Acid. Manufacturing process of aspirin is when salicylic acid is treated with acetic anhydride, causing a chemical reaction that turns salicylic acid's hydroxyl group into an ester group R-OH -> R-OCOCH3.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Cellulose Powder - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Layout

An insoluble dietary fiber that is tasteless, odorless & colorless powder produced from naturally occurring components of plants. It does not dissolve in water and can be found in whole grain products. It tends to absorb water and other liquids and helps to flush impurities from the body. It is most often marketed as a powder, is reasonably priced. Cellulose today is mainly obtained from wood pulp and cotton. Powdered cellulose is made by cooking raw plant fiber—usually wood—in various chemicals to separate the cellulose, and then purified. Modified versions go through extra processing, such as exposing them to acid to further break down the fiber. Uses and Applications Cellulose powder is used in both powder and tablet forms. As a dietary supplement, it is often marketed as an intestinal tract cleanser or a fiber additive to water for making the digestive tract function regularly. It is often the active ingredient of products advertised to increase the daily amount of fiber, such as Citrucel, which uses a form called methylcellulose. Cellulose is also used as an ingredient in other vitamin and mineral supplements as a binding agent. These products are used by some pharmaceutical companies in the market. Powder Cellulose is used for making Enzyme Cellulose which has demand in textile industry for fabric finishing and fabric softening, in detergent industry for color brightening, softening and soil removal, in wine industry for clarification of wine, in protein industry for extraction of protein and in some more industries. It is an excellent filter aid because it precoats quickly, provides good cake stability, cleans quickly, prevents bleed-through and can be burned to reduce disposal costs. Cellulose powder used in nasal sprays is being studied as a natural alternative to chemical preservatives. Since cellulose powder is resistant to bacterial growth, it is believed to serve as an organic blocker to allergens, viruses and other bacteria. Working with the natural moisture available in the nasal passages, the cellulose powder creates a gel similar to normal mucus, which traps the allergens, preventing them from entering the bronchial system. Cellulose powder is also used in Chromatography. Demand Demand for cellulose is also rising because of the growing popularity of processed food products in China, India and other countries, and because consumers are demanding low-fat or nonfat foods that still have a creamy texture. Cellulose is in demand among industries and pharmaceuticals organizations and because of its fibrous quality, its demand is gaining pace among food industries. The Copenhagen-based company makes ingredients and enzymes using cellulose powder for food, cleaning supplies and other products.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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IV CANNULA - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics

Cannula and catheter both mean exactly the same thing– a flexible tube inserted into the body to administer or withdraw fluids or to keep another tube patent. Intravenous cannulation is a technique in which a cannula is placed inside a vein to provide venous access. Venous access allows sampling of blood as well as administration of fluids, medications, parental nutrition, chemotherapy, and blood products. In general, the smallest gauge of catheter should be selected for the prescribed therapy to prevent damage to the vessel intima and ensure adequate blood flow around the catheter, which reduces the risk of phlebitis. In an emergency situation or when patients are expected to require large volumes infused over a short period of time, the largest gauge and shortest catheter that is likely to fit the chosen vein should be used.There are four types of IV Catheter: Peripheral Catheter, Midline Peripheral Catheter ,Peripherally Inserted Central Catheter & Central Venous Catheter. Uses and Applications A venous cannula is inserted into a vein, primarily for the administration of intravenous fluids, obtaining blood samples and administering medicines. An arterial cannula is inserted into an artery, commonly the radial artery, and is used during major operations and in critical care areas to measure beat to beat blood pressure and to draw repeated blood samples. IV Cannula has veterinary use, nasal or oral use too. Cannula can also be used for piercing. The common uses are rapid transfusion of blood, transfusion of IV drugs. Paediatric patients or adults with small veins undergoing long term medication or blood transfusion are subjected to IV Cannula. It is also used on oncology patients undergoing Chemotherapy. Market Survey IV Cannula is amongst the most extensively used medical disposables. Healthcare professionals represent the largest end use market for cannulae. Worldwide market for IV Cannula is driven by an aging population and related rise in healthcare demand. . The Present demand of Disposable IV Cannula is being adequately met by indigenous production. In increasing awareness in health care and like diseases and improvement in per capita income is expected to create further growth in demand of disposable IV Cannula. The use of IV Cannula is becoming more popular due to following advantages: IV Cannula have lower coefficient of thermal expansion and hence have greater accuracy & It is unbreakable. With the unhealthy living style prevailing among people, diseases are spreading at a high rate, and consequently demand of this product is increasing too. So, there is much scope and profit for entrepreneurs in establishing this business. Few Indian Major Players are as under: La Medical Devices Ltd. Lifeline Injects Ltd. Sangam Health Care Products Ltd. Span Medicals Ltd. Surgiplast Ltd.
Plant capacity: 300000 Pcs./Day Plant & machinery: Rs.804 Lakhs
Working capital: N/AT.C.I: Rs.2373 Lakhs
Return: 28.00%Break even: 36.00%
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IV CANNULA - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics

Cannula and catheter both mean exactly the same thing– a flexible tube inserted into the body to administer or withdraw fluids or to keep another tube patent. Intravenous cannulation is a technique in which a cannula is placed inside a vein to provide venous access. Venous access allows sampling of blood as well as administration of fluids, medications, parental nutrition, chemotherapy, and blood products. In general, the smallest gauge of catheter should be selected for the prescribed therapy to prevent damage to the vessel intima and ensure adequate blood flow around the catheter, which reduces the risk of phlebitis. In an emergency situation or when patients are expected to require large volumes infused over a short period of time, the largest gauge and shortest catheter that is likely to fit the chosen vein should be used.There are four types of IV Catheter: Peripheral Catheter, Midline Peripheral Catheter ,Peripherally Inserted Central Catheter & Central Venous Catheter. Uses and Applications A venous cannula is inserted into a vein, primarily for the administration of intravenous fluids, obtaining blood samples and administering medicines. An arterial cannula is inserted into an artery, commonly the radial artery, and is used during major operations and in critical care areas to measure beat to beat blood pressure and to draw repeated blood samples. IV Cannula has veterinary use, nasal or oral use too. Cannula can also be used for piercing. The common uses are rapid transfusion of blood, transfusion of IV drugs. Paediatric patients or adults with small veins undergoing long term medication or blood transfusion are subjected to IV Cannula. It is also used on oncology patients undergoing Chemotherapy. Market Survey IV Cannula is amongst the most extensively used medical disposables. Healthcare professionals represent the largest end use market for cannulae. Worldwide market for IV Cannula is driven by an aging population and related rise in healthcare demand. . The Present demand of Disposable IV Cannula is being adequately met by indigenous production. In increasing awareness in health care and like diseases and improvement in per capita income is expected to create further growth in demand of disposable IV Cannula. The use of IV Cannula is becoming more popular due to following advantages: IV Cannula have lower coefficient of thermal expansion and hence have greater accuracy & It is unbreakable. With the unhealthy living style prevailing among people, diseases are spreading at a high rate, and consequently demand of this product is increasing too. So, there is much scope and profit for entrepreneurs in establishing this business. Few Indian Major Players are as under: La Medical Devices Ltd. Lifeline Injects Ltd. Sangam Health Care Products Ltd. Span Medicals Ltd. Surgiplast Ltd.
Plant capacity: 300000 Pcs./Day Plant & machinery: Rs.804 Lakhs
Working capital: N/AT.C.I: Rs.2373 Lakhs
Return: 28.00%Break even: 36.00%
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Information
  • One Lac / Lakh / Lakhs is equivalent to one hundred thousand (100,000)
  • One Crore is equivalent to ten million (10,000,000)
  • T.C.I is Total Capital Investment
  • We can modify the project capacity and project cost as per your requirement.
  • We can also prepare project report on any subject as per your requirement.
  • Caution: The project's cost, capacity and return are subject to change without any notice. Future projects may have different values of project cost, capacity or return.

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