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DEXTROSE SALINE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Layout

capacity (per day): 5000 Bottles of 5% Dextrose Saline 1000 Bottles of 10% Dextrose Saline 1000 Bottles of 25% Dextrose
Plant capacity: -Plant & machinery: Rs. 32 Lakhs
Working capital: -T.C.I: Rs. 180 Lakhs
Return: 57.00%Break even: 29.00%
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GLUCOSE SALINE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economic

Dextrose is a carbohydrate caloric agent. Glucose, also known as dextrose, is a simple sugar that can be found in nature and are chemically identical. Dextrose is simply in lay terms sugar water and is generally used in those patients who have a very low blood glucose level or are unable to eat for some reason. It is a short term treatment generally. D5NS (Dextrose 5% in normal saline) is hypertonic, meaning it has a higher solute concentration than tissues, so it can be used to help draw fluids out of oedematous (fluid-swollen) tissues. Dextrose (glucose) 5% and normal saline (sodium chloride or common table salt 8.5 grams per 100 ml of distilled water), have the same tonicity or concentration of the rest of the body fluids, that is, they will do no harm to the rest of the fluids of the body whereas Saline or 9%NS IV solution is used as the universal fluid replacement in dehydrated individuals, it is the same composition as the body's normal fluid and most IV medications can safely be mixed with or push through saline. Dosage of dextrose depends on the age, weight, clinical condition, and fluid, electrolyte, and acid-base balance of the patient. Dextrose is readily metabolized; it increases blood glucose concentrations and provides calories. Dextrose may decrease body protein and nitrogen losses, promote glycogen deposition, and decrease or prevent ketosis if sufficient doses are given. Since dextrose is usually metabolized to carbon dioxide and water, administration of a solution of dextrose and water is equivalent to providing the same volume of free water. Following oral administration, dextrose, a monosaccharide, is rapidly absorbed from the small intestine principally by an active mechanism. In patients with hypoglycemia, increases in blood glucose concentration usually occur within 10–20 minutes and peak at about 40 minutes after oral administration of dextrose. In medicine, saline (also saline solution) is a general term referring to a sterile solution of sodium chloride (NaCl, more commonly known as salt) in water but is only sterile when it is to be placed intravenously; otherwise, a saline solution is a salt water solution. Thus, an intravenous infusion, a saline solution is typically mixed with dextrose or glucose to reduce any complications from infusing saline solution and to reduce the amount of sodium circulating through the blood stream. This works particularly well as a water and nutrient supplement to sustain hospitalized patients who are unable to eat or drink or who have suffered dehydration from severe vomiting or diarrhea. In present era, people are becoming very health conscious as the infection through air, water, food is prevailing across the country to the maximum. As hospitals are increasing day by day, doctors also prefer to use distilled water ampoules. There are several in organized and private sectors are engaged in the manufacturing of different grade dextrose saline solution. The demand growth is about 5% in each and every year. The entire demand gap is fulfilled by the domestic manufacturers. There is scope of dextrose saline bottle. New entrepreneur may launch in this field will be successful. Few Indian Major Players are as under: Gulshan Polyols Ltd. Kamala Sugar Mills Ltd. Origin Agrostar Ltd. Rai Agro Inds. Ltd. Sanjeevanee Pharmaceuticals Ltd. Santosh Starch Ltd. Sukhjit Starch & Chemicals Ltd. Unique Sugars Ltd. Universal Starch-Chem Allied Ltd.
Plant capacity: 3600 Thousand Bottles Each Bottles 500 ml/AnnumPlant & machinery: 66 Lakhs
Working capital: -T.C.I: Cost of Project : 153 Lakhs
Return: 42.00%Break even: 59.00%
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Saline and Dextrose Fluid (IV Fluid) BFS Technology

As part of the millennium development goals (MDGs), governments in the region have developed strategies directed at reducing the negative impact of diseases like HIV, Malaria or Tuberculosis on the society by 2015. The strategies include halting and reversing the spread of HIV/AIDS, reducing the level of malaria infection, and reducing prevalence and death rates associated with tuberculosis. Severe malaria results into high fever, which requires the use of Intravenous Fluids as the first line of treatment. However, due to limited local production and supply, the fluids are comparatively expensive compared to other developed world where they are affordable and readily available. In India, local monopolies and distributors that sell the fluids very costly import 98% of the IV Fluids. Faced with the current factual situation Govt. Oriented organization planned to establish Intravenous Project to locally produce and supply this very essential product to the healthcare sector as a noble contribution in improving healthcare services. The project expects to promote the common good in the Eastern Region, to reduce the current high level of deaths from 9-14% of in-patient visits in hospitals and health facilities. In medicine, saline (also saline solution) is a general phrase referring to a sterile solution of sodium chloride (NaCl, more commonly known as salt) in water, but is only sterile when it is to be placed parenterally (such as intravenously); otherwise, a saline solution is a salt water solution. The sterile solution is typically used for intravenous infusion, rinsing contact lenses, nasal irrigation, and often used to clean a new piercing. It is also a good medium to store an avulsed ("knocked out") tooth until it can be re-implanted by a dentist. Saline solutions are available in various formulations for different purposes. Salines are also used in cell biology, molecular biology, and biochemistry experiments. Uses & Applications There are four main ranges of application of highly specialized intravenous infusion solutions: • Treatment of discarded water and electrolyte metabolism, especially in severe cases. • Therapy of acid base in balances. • The volume substitution and volume replacement in surgery of accident victim suffering blood lose. • Paratrial nutrition for severally ill and post-operative patients. • Aqueous isotonic injection (5%) of dextrose is given as intravenous injections to increase the column of circulating blood in the shocks and hemorrhages and to counteract dehydration. Dextrose solution is used during post operative period when sodium extraction is reduced. • Dextrose solution with concentration of 10-15% is used as diuretic for increase in urine flow. • Dextrose solution of 5% normal salmic is used for restarting fluid volume in circulation of an emergency as in accidents. • Saline solution is used when large amount of sodium has been lost by vomiting or by gastric or intestinal duodenal aspiration or through analimucation fistuala. • Dextrose monohydrate is used as supplement to cow's milk in part of feeding. • Hypertonic dextrose solution (25-50%) is in medical treatment partly because they are believed to strengthen heart muscles. • Hypertonic solutions are used in intravenous injection to relieve intractable pressure in patient with hydrocephalus and meningitis. Market Survey Our system of medicine like Ayurveda were well established and schools and hospitals with treatises and instruction manuals were in wide use. The growth of I.V. fluid manufacturing was faster than the growth rate of drugs. I.V fluids are the solutions applied directly to the vein of a patient who suffer from the weaknesses due to the deficiency of body fluids. These IV fluids are the best alternative which can yield sudden result in the health of a patient by replenishing the body fluids. Liquid glucose and dextrose are being produced in the organized sector. Glucose is produced in solid as well as in liquid form and dextrose is in anhydrous and monohydrous form. The gap between the production and consumption of liquid glucose is removed by the import. I.V. fluid demand is normally linked to the number of hospital beds. Observations show that 18 bottles of I.V. fluids are consumed per bed per month in the country. The demand is estimated to increase at a rate of 9 to 12% per annum. The present demand level is estimated to be around 2200 lakh bottles per annum. Areas with high population density and average temperatures are major consumption areas of I.V. fluids. Demand is high Uttar Pradesh, Rajasthan, Haryana, Bihar, Madhya Pradesh and West Bengal. North India alone account for one third of the total demand in the country.
Plant capacity: 48000 Bottles/day(500 ml)Plant & machinery: 253 Lakhs
Working capital: -T.C.I: Cost of Project: 834 Lakhs
Return: 29.00%Break even: 52.00%
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Saline and Dextrose Fluid (IV Fluid) BFS Technology

As part of the millennium development goals (MDGs), governments in the region have developed strategies directed at reducing the negative impact of diseases like HIV, Malaria or Tuberculosis on the society by 2015. The strategies include halting and reversing the spread of HIV/AIDS, reducing the level of malaria infection, and reducing prevalence and death rates associated with tuberculosis. Severe malaria results into high fever, which requires the use of Intravenous Fluids as the first line of treatment. However, due to limited local production and supply, the fluids are comparatively expensive compared to other developed world where they are affordable and readily available. In India, local monopolies and distributors that sell the fluids very costly import 98% of the IV Fluids. Faced with the current factual situation Govt. Oriented organization planned to establish Intravenous Project to locally produce and supply this very essential product to the healthcare sector as a noble contribution in improving healthcare services. The project expects to promote the common good in the Eastern Region, to reduce the current high level of deaths from 9-14% of in-patient visits in hospitals and health facilities. In medicine, saline (also saline solution) is a general phrase referring to a sterile solution of sodium chloride (NaCl, more commonly known as salt) in water, but is only sterile when it is to be placed parenterally (such as intravenously); otherwise, a saline solution is a salt water solution. The sterile solution is typically used for intravenous infusion, rinsing contact lenses, nasal irrigation, and often used to clean a new piercing. It is also a good medium to store an avulsed ("knocked out") tooth until it can be re-implanted by a dentist. Saline solutions are available in various formulations for different purposes. Salines are also used in cell biology, molecular biology, and biochemistry experiments. Uses & Applications There are four main ranges of application of highly specialized intravenous infusion solutions: • Treatment of discarded water and electrolyte metabolism, especially in severe cases. • Therapy of acid base in balances. • The volume substitution and volume replacement in surgery of accident victim suffering blood lose. • Paratrial nutrition for severally ill and post-operative patients. • Aqueous isotonic injection (5%) of dextrose is given as intravenous injections to increase the column of circulating blood in the shocks and hemorrhages and to counteract dehydration. Dextrose solution is used during post operative period when sodium extraction is reduced. • Dextrose solution with concentration of 10-15% is used as diuretic for increase in urine flow. • Dextrose solution of 5% normal salmic is used for restarting fluid volume in circulation of an emergency as in accidents. • Saline solution is used when large amount of sodium has been lost by vomiting or by gastric or intestinal duodenal aspiration or through analimucation fistuala. • Dextrose monohydrate is used as supplement to cow's milk in part of feeding. • Hypertonic dextrose solution (25-50%) is in medical treatment partly because they are believed to strengthen heart muscles. • Hypertonic solutions are used in intravenous injection to relieve intractable pressure in patient with hydrocephalus and meningitis. Market Survey Our system of medicine like Ayurveda were well established and schools and hospitals with treatises and instruction manuals were in wide use. The growth of I.V. fluid manufacturing was faster than the growth rate of drugs. I.V fluids are the solutions applied directly to the vein of a patient who suffer from the weaknesses due to the deficiency of body fluids. These IV fluids are the best alternative which can yield sudden result in the health of a patient by replenishing the body fluids. Liquid glucose and dextrose are being produced in the organized sector. Glucose is produced in solid as well as in liquid form and dextrose is in anhydrous and monohydrous form. The gap between the production and consumption of liquid glucose is removed by the import. I.V. fluid demand is normally linked to the number of hospital beds. Observations show that 18 bottles of I.V. fluids are consumed per bed per month in the country. The demand is estimated to increase at a rate of 9 to 12% per annum. The present demand level is estimated to be around 2200 lakh bottles per annum. Areas with high population density and average temperatures are major consumption areas of I.V. fluids. Demand is high Uttar Pradesh, Rajasthan, Haryana, Bihar, Madhya Pradesh and West Bengal. North India alone account for one third of the total demand in the country.
Plant capacity: 48000 Bottles/day(500 ml)Plant & machinery: 253 Lakhs
Working capital: -T.C.I: Cost of Project: 834 Lakhs
Return: 29.00%Break even: 52.00%
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Saline and Dextrose Fluid (IV) - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

The growth of I.V. fluid manufacturing was faster than the growth rate of drugs. These IV fluids are the best alternative which can yield sudden result in the health of a patient by replenishing the body fluids. Liquid glucose and dextrose are being produced in the organized sector. The gap between the production and consumption of liquid glucose is removed by the import. I.V. fluid demand is normally linked to the number of hospital beds. Observations show that 18 bottles of I.V. fluids are consumed per bed per month in the country. The demand is estimated to increase at a rate of 9 to 12% per annum. The present demand level is estimated to be around 2200 lakh bottles per annum. Demand is high Uttar Pradesh, Rajasthan, Haryana, Bihar, Madhya Pradesh and West Bengal. North India alone account for one third of the total demand in the country.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: 1.00%
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Production of I.V. Fluids (Saline and Dextrose). Intravenous Solution (IV) Manufacturing Business with Blow-Fill-Seal (BFS) Technology.

Fluids are given when someone's body fluid volume falls. There are a number of things which can cause a drop in fluid volume. Vomiting and diarrhea are a classic example, which is why people are encouraged to drink fluids when they are sick, to keep their fluid volume stable. Another cause is blood loss, which causes problems both because people lose blood products, and because they experience a loss in fluid volume. Electrolyte levels in the blood can also become unstable as a result of rapid changes in fluid volume, in which case intravenous fluids can be used to restore the balance. Intravenous fluids are fluids which are intended to be administered to a patient intravenously, directly through the circulatory system. These fluids must be sterile to protect patients from injury, and there are a number of different types available for use. Many companies manufacture packaged intravenous fluids, as well as products which can be mixed with sterile water to prepare a solution for intravenous administration. Intravenous fluids can be broken into two broad groups. Crystalloids such as saline solutions contain a solution of molecules which can dissolve in water. When crystalloids are administered, they tend to create low osmotic pressure, allowing fluid to move across the blood vessels, and this can be linked with edema. Colloids contain particles which are not soluble in water, and they create high osmotic pressure, attracting fluid into the blood vessels. Blood is an example of a commonly administered intravenous colloid. Infusion therapy as a basic toll of modern medical care enables the physician to restore and stabilize homeostasis states quickly and completely. In nursing homes and hospital where patients are suffering from acute dehydration or considerable debilitating conditions, the intra venous fluids are used as I.V. drips. The basic function of I.V. fluids is to replenish the body fluids. Although there are a number of I.V. fluids but generally three types of I.V. fluids are used in hospitals as I.V. drips. Uses and Applications There are main ranges of application of highly specialized intravenous infusion solutions: • Treatment of discarded water and electrolyte metabolism, especially in severe cases. • Therapy of acid base in balances. • The volume substitution and volume replacement in surgery of accident victim suffering blood loss. • Paratral nutrition for severally ill and post-operative patients. • Aqueous isotonic injection (5%) of dextrose is given as intravenous injections to increase the column of circulating blood in the shocks and haemorrhages and to counteract dehydration. When it is desired to replace excessive salt loss also glucose is injected along with sodium chloride. Intravenous fluids can also be used as a route of medication administration. If a doctor wants to delI.V.er a small amount of medication over an extended period of time, it can be dissolved in a bag of intravenous fluids and set on an infusion pump which delivers the medicated fluid directly into the blood. They are also commonly used to assist with surgical recovery; people who receive fluids after surgery tend to experience better recovery than people who do not. Intravenous Fluids Market is expected to witness growth of international market with respect to advancements and innovations including development history, competitive analysis and regional development forecast. The growth of the global intravenous solutions market is driven by several factors. The increasing incidence of gastrointestinal disorders, diabetes, and cancer is one of the major factors that are expected to increase the rate of adoption of intravenous solutions among consumers. The rising popularity of intravenous vitamin C therapy in cancer treatment is one of the major trends in the intravenous solutions market. The intravenous vitamin C solution has been observed to have an increased toxicity to cancer cells and improve the patients' quality of life. Intravenous fluids are extensively used to treat electrolyte imbalances, maintain fluid balance, and replace fluid losses. These fluids are dispensed in volumes ranging from 25-1,000 milliliters and are available in either plastic bags or glass bottles. A complete mixture of all essential nutrients is also available in multi-chamber bags, and these bags are gaining immense popularity among numerous end-users. The global Intravenous (I.V.) solutions market was valued at USD 6.9 billion in 2015 and is projected to grow at a CAGR of 7.8% over the forecast period. The emergence of this market is attributed to the fast growing geriatric population and prevalence of malnutrition in the elderly and pediatric population. Blow-Fill-Seal (BFS) Technology In blow-fill-seal (BFS) technology, which is a form of advanced aseptic manufacturing, the container is formed, filled, and sealed in one continuous, automated system. A primary advantage of this technology is reducing human intervention, which reduces the risk of microbial contamination and foreign particulates. BFS has long been used in liquid pharmaceutical applications, including small containers, such as ophthalmic and respiratory drug ampoules, as well as larger volume containers, such as saline or dextrose solutions. More recently, BFS technology has been expanding into injectable and into biologics, including vaccines and monoclonal antibodies (mAbs). Advantages of BFS Technology: • Blow-fill-seal technology enables the manufacture of preservative-free single-unit doses. PreservatI.V.es are recognized as potentially harmful to the sensitive mucosae of the eyes, nose, and lungs, so this is an enormous benefit to sensitive patients. • Another advantage of unit-doses is that they ensure that the patient takes the correct amount of product, especially when dealing with highly potent compounds, i.e. those therapeutically active at a low concentration. • Sterile unit-doses are portable and easy to use individually, excellent properties for today’s active lifestyles. Blow-fill-seal (BFS) single doses are an ideal solution for use in ophthalmology, respiratory diseases, rhinology, antisepsis and wound care. • Blow-fill-seal technology reduces personnel intervention making it a more robust method for the aseptic preparation of sterile pharmaceuticals. BFS is used for the filling of vials for parenteral preparations and infusions, eye drops, and inhalation products. Generally the plastic containers are made up of polyethylene and polypropylene. Polypropylene is more commonly used to form containers which are further sterilised by autoclaving as polypropylene has greater thermostability. • Blow Fill and Seal technology is mainly used for pharmaceutical solutions. The examples of pharmaceutical solutions that can be packaged are injectable solutions, antibiotics, ophthalmological drops, suspensions, infusion solutions, solutions for dialysis, solutions for irrigation and solutions for hemofiltration. The basic concept of BFS is that a container is formed, filled, and sealed in a continuous process without human intervention, in a sterile enclosed area inside a machine. Thus this technology can be used to aseptically manufacture sterile pharmaceutical liquid dosage forms. The process is multi-stepped: first, pharmaceutical-grade plastic resin is vertically heat extruded through a circular throat to form a hanging tube called the parison. This extruded tube is then enclosed within a two-part mould, and the tube is cut above the mould. The mould is transferred to the filling zone, or sterile filling space, where filling needles (mandrels) are lowered and used to inflate the plastic to form the container within the mould. Following the formation of the container, the mandrel is used to fill the container with liquid. Following filling the mandrels are retracted and a secondary top mould seals the container. All actions take place inside a sterile shrouded chamber inside the machine. The product is then discharged to a non-sterile area for labeling, packaging and distribution. The process begins with the Extrusion of plastic granules in the form of a hot hollow pipe of molten plastic called a parison. The following step is the Blow moulding of the container from the plastic granule. The parison is closed between the mould, and the container gets formed either by blowing sterile compressed air or by vacuum or by using vacuum as well as blowing. The container assumes the shape of the cavity in the mould. The container thus produced is open from the top and in its top part, the plastic is still hot and in molten state until the subsequent steps of filling and container sealing. The subsequent step is filling of the formed container from the top, which is still open (and still in a “hot molten” state). Filling nozzles enter from the top of container and filling is done. Filling nozzles are specially designed and constructed to facilitate automatic cleaning and automatic sterilization. Additional functions of filling nozzles are to blow the bottles and also to provide an exhaust path for air in the container. The filling process can be carried out under a shower of sterile filtered air to avoid contamination during filling. The blower on the sterile air shower can have variable pressure which can be made to change automatically so as to maintain constant air pressure under various situations. The sterile air shower is validated at certain air pressure, and an automatic device can maintain the same pressure by automatically modulating the speed of the blower. The next step is sealing the top of the container, which is still open and in a hot molten state. The top gets pressed between head moulds and as a consequence, the top part of the container gets formed, sealed and at the same time, gets cooled. The result is a hermetically sealed container. The final steps are for De-flashing to remove the flash or scrap, trimming the containers and delivering the containers outside the machine. The whole process of extrusion, blowing, filling, sealing and removing scrap takes between 10 to 18 seconds depending upon the type and size of the container. The advantage of the Blow-Fill-Seal process is derived mainly from the fact that container is formed, quickly filled and sealed under protected environment automatically without human intervention. BFS Machine Professional normal saline I.V. fluids packaging machine is the latest production line with most advanced technology. It can automatically finish film feeding, printing, bag making, filling and sealing in one machine. This BFS line can be used to automatically fill 50-5000ml general solution, special solution, dialysis solution, parenteral nutrition, Antibiotics, Irrigation and Disinfectant solution etc. Features: 1. 100% film utilization: No waste edge between bags, reducing both material and energy consumption. 2. Special I.V. bag design: each bag saves 10mm film than others. 3. Reliable heating and welding system: Leakage rate less than 0.03%. 4. Quick changeover: 0.5-1 hour to switch from one size to another. 5. Stable transmission system: only needs 1 control system, 1 HMI and 1 operator. 6. Safe filling nozzle: No solution overflows, no particles generation. 7. Auto faulty rejection system detected by the machine. 8. Production line length is reduced by 1/3, both workshop and air conditioning and cleaning area are reduced by 1/3, greatly reducing the initial investment and future running cost. 9. Simple structure, more stable and reliable performance. Tags I.V. Fluid Manufacturing Industry, I.V. Fluids Manufacturing Project Report, I.V. Fluids Manufacturing Process, Project Report for I.V. Fluid Plant, I.V. Fluids Manufacturing Equipment, IV Fluids Manufacturing Project Report, I.V. Fluid Manufacturing Plant in India, I.V. Fluids Manufacture, I.V. Fluid Production Plant, I.V. Fluid and Dialysis Solution Manufacturing, Project Report on Dextrose Saline (IV Fluid) Production, I.V. Fluids Production, I.V. Fluid Manufacturing Unit, IV Fluid Manufacturing Business, Pharma Manufacturing Unit in India, Pharmaceutical Company, Intravenous Fluid Production, Project Report on I.V. Fluid, IV Fluid Manufacturing Unit in India, I.V. Fluids Manufacturing Process, I.V. Fluids Manufacturing Equipment, Manufacturing Plant for I.V. Fluid, I.V. Fluid Manufacturing Machine, I.V. Fluids Manufacturing Project Report, IV Fluid Manufacturing Business, Manufacturing Plan of Intravenous Fluid, How to Start I.V. Fluid Production Business, I.V. Solution Manufacturing with BFS Technology, Blow-Fill-Seal Technology, Saline and Dextrose Fluid (IV Fluid) BFS Technology, Blow Fill Seal(BFS) Technology, Project Report on I.V. Fluid (BFS Technology), I.V. Fluid with BFS, Blow-Fill-Seal Machinery, I.V. Fluid Manufacturing using Blow–Fill–Seal Technology, I.V. Fluid Manufacturing project ideas, Projects on Small Scale Industries, Small scale industries projects ideas, IV Fluid Manufacturing Based Small Scale Industries Projects, Project profile on small scale industries, How to Start I.V. Fluid Manufacturing Industry in India, I.V. Fluid Manufacturing Projects, New project profile on I.V. Fluid Manufacturing industries, Project Report on IV Fluid Manufacturing Industry, Detailed Project Report on IV Fluid Manufacturing, Production of Intravenous Sugar Solution (Dextrose Solution), Saline and Dextrose Fluid (iv Fluid) BFS Technology, Production of Intravenous Sugar Solution, Project Report on I.V. Fluid Manufacturing, Pre-Investment Feasibility Study on IV Solution Manufacturing with BFS Technology, Techno-Economic feasibility study on I.V. Solution Manufacturing with BFS Technology, Feasibility report on I.V. Solution Manufacturing with BFS Technology, Free Project Profile on I.V. Solution Manufacturing with BFS Technology, Project profile on I.V. Solution Manufacturing with BFS Technology, Download free project profile on IV Solution Manufacturing with BFS Technology, Industrial Project Report, Project consultant, Project consultancy, Business guidance to clients, Startup Project for I.V. Solution Manufacturing with BFS Technology, Production of I.V. Fluids (Saline and Dextrose), Intravenous Solution (IV) Manufacturing Business with Blow-Fill-Seal (BFS) Technology
Plant capacity: 48,000 Bottles/Day 500 ml each bottlePlant & machinery: 253.00 Lakhs
Working capital: N/AT.C.I: Cost of Project 834.00Lakhs
Return: 29.00%Break even: 52.00%
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Saline and Dextrose Fluid (IV)

Saline is a general phrase referring to a sterile solution of sodium chloride in water, but is only sterile when it is to be placed parenterally; otherwise, a saline solution is a salt water solution. The sterile solution is typically used for intravenous infusion, rinsing contact lenses, nasal irrigation, and often used to clean a new piercing. Dextrose Solution (5%) is an isotonic solution and supplies calories to human body instantaneously without disturbing the electrotype balance. The global Intravenous (IV) solutions market was valued at USD 6.9 billion in 2015 and is projected to grow at a CAGR of 7.8% over the forecast period. And is expected to reach a value of USD 13.79 billion by 2024. As a whole there is a good scope for new entrepreneur to invest in this business. Few Indian major players are as under • Amanta Healthcare Ltd. • Axa Parenterals Ltd. • Infutec Healthcare Ltd. • Kokad Pharmaceutical Laboratories Ltd. • Parenteral Drugs (India) Ltd. • Parenteral Surgicals Ltd.
Plant capacity: Dextrose IV Fluid (100 ml Size) : 7800 Bottles/Day Dextrose-Sodium Chloride IV Fluid (250 ml Size): 7200 Bottles/Day Sodium Chloride IV Fluid (500 ml Size): 6200 Bottles/Day Ciprofloxacin (100 gm Size) Bye Product: 250 Bottles/Day FluconazolPlant & machinery: Rs 2281 lakhs
Working capital: -T.C.I: Cost of Project: Rs 3200 lakhs
Return: 28.00%Break even: 34.00%
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Glucose Saline

Glucose, also known as dextrose, is a simple sugar that can be found in nature and are chemically identical. Dextrose may decrease body protein and nitrogen losses, promote glycogen deposition, and decrease or prevent ketosis if sufficient doses are given. Since dextrose is usually metabolized to carbon dioxide and water, administration of a solution of dextrose and water is equivalent to providing the same volume of free water. Dextrose is readily metabolized; it increases blood glucose concentrations and provides calories. Dextrose may decrease body protein and nitrogen losses, promote glycogen deposition, and decrease or prevent ketosis if sufficient doses are given. Since dextrose is usually metabolized to carbon dioxide and water, administration of a solution of dextrose and water is equivalent to providing the same volume of free water. Following oral administration, dextrose, a monosaccharide, is rapidly absorbed from the small intestine principally by an active mechanism. It used for balancing the body fluid and it is added to the human body to balance the body fluid by injection which will recover fatality of the human being and recover the inside body pressure. Treatment of discarded water and electrolyte metabolism, especially in severe cases. Therapy of acid base in balances. The volume substitution and volume replacement in surgery of accident victim suffering blood lose. Arenteral nutrition for severally ill and post-operative patients. Saline is also often used for nasal washes to relieve some of the symptoms of the common cold. The solution exerts a softening and loosening influence on the mucus to make it easier to wash out and clear the nasal passages for both babies and adults. In this case "home-made" saline may be used: this is made by dissolving approximately half a teaspoon of table salt into 8 ounces (approx. 240ml) of clean tap water. The global intravenous solutions market reached a value of US$ 8.5 Billion in 2019. IV solutions and electrolytes are mainly used for fluid resuscitation, routine maintenance, replacement, and redistribution. The Market size value in 2020 is USD 86.2 million and Revenue forecast in 2025 is USD 121.7 million is expected to exhibit a CAGR of 7.1% from 2018 to 2025. As a whole any entrepreneur can venture in this project without risk and earn profit. Few Indian major players • Amanta Healthcare Ltd. • Baxter Pharmaceuticals India Pvt. Ltd. • Bayer Pharmaceuticals Pvt. Ltd. • Denis Chem Lab Ltd. • Meridian Enterprises Pvt. Ltd. • Pfizer Healthcare India Pvt. Ltd. • Pfizer Ltd. • Pharmacia Healthcare Ltd. • Shree Krishna Keshav Laboratories Ltd. • Vikrant Pharmaceuticals Ltd.
Plant capacity: 200000 Bottles/ dayPlant & machinery: Rs. 2170 Lakhs
Working capital: -T.C.I: Cost of Project: Rs. 4083 Lakhs
Return: 25.00%Break even: 37.00%
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Business & Investment Opportunity in Manufacturing of Glucose Saline. IV fluids Used in Hospitals, Nursing Homes

Introduction: IV fluids are almost universally administered to patients undergoing major operations, where they meet the need to retain intravascular volume at a time when it may be exhausted due to preoperative fasting, surgical blood loss, evaporation, urinary excretion, Anesthesia-induced vasodilation, fluid loss into the third room, and inflammatory mediator-induced albumin transcapillary leak Water, sugar, and salt are all essential for the body to work properly. Intravenous fluids (also known as 'IV' fluids) are liquids that are supplied to replace water, sugar, and salt that you may need if you are sick or undergoing surgery and are unable to eat or drink. IV fluids are injected directly into a vein with a drip. Related Project: GLUCOSE SALINE Intravenous therapy (also known as IV therapy) is a surgical procedure that involves injecting fluids, drugs, and nutrients into a patient's vein. Intravenous administration is widely used to rehydrate or provide nutrients to those who are unable to absorb food or water through their mouth. Since drugs and fluid replacement are delivered directly into the circulatory system and therefore easily spread, the intravenous route is the quickest way to administer them in the body. As a result, intravenous administration is often used for the administration of certain recreational drugs. Many therapies are given as a "bolus," or one-time injection, but they can also be given as an infusion or drip over time. Intravenous treatment administration or the placement of an intravenous line ("IV line") for later use is a technique that can only be done by a trained physician. Uses of Glucose Saline: In clinical medicine, intravenous solutions are often used to replace and maintain body fluids. In general, intravenous fluids are used as I.V drips for patients in nursing homes and hospitals that are dehydrated or have severe disabling conditions. Related Videos: Pharmaceutical, Drugs, Fine Chemicals, Bulk Drug Intermediates, Pharmaceutical Drugs, Pharma Drug Ingredients Intermediates, Pharmaceutical Bulk Drugs The body fluids are replanished with these intravenous fluids. Intravenous fluids (often abbreviated as 'IV' fluids) are liquids provided to replace water, sugar, and salt that you may need if you are sick or undergoing surgery and are unable to eat or drink normally. IV fluids are injected directly into a vein with a drip. IV rehydration was once a common method for athletes. Unless there is a medical exception, the World Anti-Doping Agency bans intravenous injections of more than 100mL every 12 hours. In addition to the risks associated with IV treatment, the US Anti-Doping Agency notes that "IVs can be used to change blood test outcomes." Related Books: Pharmaceutical, Drugs, Proteins Technology Handbooks Cover urine test results (by dilution) or administer banned substances in a way that would be removed from the body more easily in order to beat an anti-doping test (such as hematocrit when EPO or blood doping is used). Market Outlook: There are many varieties of intravenous solutions on the market, including isotonic, hypertonic, and hypotonic. Isotonic solutions are made up of normal saline (0.9 NaCl) and are used to substitute extracellular fluid in the treatment of hypernatremia. As electrolyte replenishers, hypotonic intravenous solutions of 0.45 percent NaCl are used. Increased prevalence of chronic and acute diseases, rise in the geriatric population, increase in strategic alliances between manufacturers to expand their product range and geographical presence, expansion in the pharmaceutical industry are all major drivers of the global intravenous solutions market. Market Research: - Market Research Report A rise in the demand for intravenous solutions in developed economies, as well as an increase in health-care spending however, the global intravenous solution market is expected to be restrained by factors such as a strict regulatory environment and high fluid maintenance costs. In the global economy, the intravenous (IV) solution market was rapidly growing and achieving a high market value. Intravenous solutions industry developments are supplying a variety of intravenous solutions to meet the needs of various types of patients. Key Players: • Amanta Healthcare Ltd. • Baxter Pharmaceuticals India Pvt. Ltd. • Bayer Pharmaceuticals Pvt. Ltd. • Denis Chem Lab Ltd. • Meridian Enterprises Pvt. Ltd. • Pfizer Healthcare India Pvt. Ltd. • Pfizer Ltd. • Pharmacia Healthcare Ltd. • Shree Krishna Keshav Laboratories Ltd. • Vikrant Pharmaceuticals Ltd. • Wockhardt Health Care Ltd. For More Details: - https://www.entrepreneurindia.co/project-and-profile-details/Business%20Plan%20of%20Glucose%20Saline%20Manufacturing
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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Dextrose Saline

Normal saline (NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, about 300 mOsm/L or 9.0 g per liter. Aless commonly, this solution is referred to as physiological saline or isotonic saline, neither of which is technically accurate. NS is used frequently in intravenous drips (IVs) for patients who cannot take fluids orally and have developed or are in danger of developing dehydration or hypovolemia. For medical purposes, saline is often used to flush wounds and skin abrasions. Normal saline will not burn or sting when applied. Saline is also used in I.V. therapy, intraveno supplying extra water to rehydrate patients or supplying the daily water and salt needs ("maintenance" needs) of a patient who is unable to take them by mouth. Dextrose (D-glucose, corn sugar, starch sugar, blood sugar and grape sugar) is by far the most abundant sugar in nature and occurs either in the Free State (monosaccharide form) or chemically linked with other sugar varieties. In the Free State, it occurs in substantial quantities in honey, fruits, and berries. As a polymer of anhydrodextrose units, it occurs in starch, cellulose, and glycogen. Sucrose is a disaccharide of dextrose and fructose. Commercial production of dextrose by hydrolysis of starch yields white crystalline sugars that are either anhydrous (C6H12O6) or hydrated (C6H12O6H2O). Dextrose hydrate with its one molecule of water of crystallization per molecule of sugar, separates from concentrated solutions at <50°C. Anhydrous D-glucose does not contain water of crystallization and separates at 50-115°C. Another anhydrous form, B-D-glucose separates, if crystallization is carried out at temperatures >110-115°C. • Dextrose solution is used during post-operative period when sodium extraction is reduced. • Dextrose solution with concentration of 10-15% is used as di-urietic for increase in urine flow. • Dextrose solution of 5% normal salmicis used for restarting fluid volume in circulation of an emergency as in accidents with raemdrrhage. • Saline solution is used when large amount of sodium has been lost by vomiting or by gastric or intestinal duodenal aspiration or through analimucationfistuala. • Dextrose monohydrate is used as supplement to cow's milk in part of feeding. The increasing prevalence of chronic diseases is expected to drive the growth of the market. It has been forecasted that cancer will rapidly increase by approximately 70% in the next few decades. As per the World Cancer Research Fund International, stomach cancer is one of the top 5 cancers with 952,000 new cases diagnosed in 2012. These patients are ‘nil by mouth’ and have to rely on total parenteral nutrition (TPN) for survival. Intravenous (IV) solutions are fluids which are intended to be administered to a patient directly into the venous circulation. These fluids are sterile fluids which protects patients at the time of serious dehydration. There are various type of IV solutions available for use in the market. Many companies manufactures packaged intravenous fluids or products or compounds which can be mixed with sterile water to prepare a solution for intravenous administration. The market for Intravenous (IV) Solution is expected to reach USD 11,511.2 million by 2022 and is expected to grow at a CAGR of 7.69% during the forecast period 2016-2022. The factors which drive the growth of the market are the rising prevalence of chronic diseases, rising acceptance of vitamin C intravenous treatment therapy to treat colorectal cancer. Thus, due to demand it is best to invest in this project. Few Indian Major Players • Pfizer Healthcare India Pvt. Ltd. • Pfizer Ltd. • Pharmacia Healthcare Ltd. • Shree Krishna Keshav Laboratories Ltd. • Vikrant Pharmaceuticals Ltd. • Wockhardt Health Care Ltd.
Plant capacity: Dextrose Saline 500 ml Size:15,000 Bottles Per Day Dextrose Saline 1000 ml Size:15,000 Bottles Per DayPlant & machinery: 1148 Lakhs
Working capital: -T.C.I: Cost of Project:1542 Lakhs
Return: 25.00%Break even: 44.00%
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