I.V FLUIDS:

Overview:

This stands for intravenous therapy i.e. “intra” means “within” and “venous” means “vein” ,also called electrolyte therapy because manage the electrolyte balance. These fluids are directly administrated in the circulatory system via a needle, given when someone’s fluid volume falls e.g. in diarrhea, vomiting etc. fluids can be used as a route of medication administration. There are a number of ways to use it, some company provide packaged or some provide them mixed with sterile water (means that all the bacteria and viruses have been killed).

Types of I.V fluids:

1.       Crystalloid:

 Balanced salt/electrolyte solution; forms a true solution and is capable of passing through   semi permeable membranes. May be isotonic, hypertonic, or hypotonic e.g. normal Saline (0.9% NaCl), Lactated Ringer’s, Hypertonic saline (3, 5, & 7.5%), Ringer’s solution.

2.       Colloid:

High-molecular-weight solutions, draw fluid into intravascular compartment via oncotic pressure (pressure exerted by plasma proteins not capable of passing through membranes on capillary walls) e.g.lbumin, Hetastarch, Pentastarch (Pentaspan), Plasma, Dextran

3.       Free H2O solutions:

Provide water that is not bound by macromolecules or organelles, free to pass

through.D5W (5% dextrose in water), D10W, D20W, D50W, and Dextrose/crystalloid mixes

4.       Blood products:

whole blood, packed RBCs, FFP, cryoprecipitate, platelets, albumin. Essentially colloids.

                Commonly used I.V fluids are

 

·         Lactated ringer’s (LR)

·         normal saline(NS),

·         D5LR,

·         D5NS,

·         D5.45NS,

·         D5.25NS,

·         7.5%NS,

·         D5W,

·         6%hetastarch,

·         5% plasma protein(250 ml)

 

 

 

Methods of calculation of I.V fluids therapy

Can be calculated by three methods:

1. Holliday-Segar method.

2. Caloric method.

3. Body surface area method.

Guidelines for I.V fluids

·         Intravenous  Fluids  are  liable  to  Microbial  Growth,  contamination  of  Particulate  matter  leading  to  adverse  drug  reaction. 

·         Careful  handling  to  prevent damage  from  cracks  which  leads  to  contamination  of  fluids  meant  for  I.V administration.

·         Precautions during temporary storage, transportation and handling.

·         The  applicant  shall  make  adequate  arrangements  for  the  storage  of  drugs manufactured by him.

·         applicant  shall,  while  applying  for  license  to  manufacture  patent  or proprietary medicines

Note: IV fluids may be harmful in trauma cases

 

How NIIR Project Consultancy Services (NPCS) can help You :-

NIIR can provide project consultancy services to any budding entrepreneur, who wants to establish a IV fluids. Our Consultancy can provide the complete report covering topics like Plant Economics, Production Schedule, Land & Building, Site Development Expenses, and Working Capital Requirement etc. In order to get more information on how we can help you, please visit: http://goo.gl/mpnu8y

NIIR Project Consultancy Services helps in establishing business prospective in manufacturing different kind of I.V fluids. Detailed project report can be modified as per requirement of cost and capacity of the project. We have a state-of-the-art experience in preparing projects report on different subjects as per need.

 

 

 

We can provide you details project report, which Contains

·         Introduction

·         Properties

·         BIS (Bureau of Indian Standard) Specifications & Requirements

·         Uses & Applications

·         Present Indian Market Position

·         Expected Future Demand

·         Export & Import Statistics Data

·         Names and Addresses of Existing Units (Present Manufactures)

·         List of Plant & Machineries

·         Miscellaneous Items and Accessories

·         Instruments, Laboratory Equipments and Accessories

·         Electrification, Electric Load and Water

·         Maintenance, Suppliers/Manufacturers of Plant and Machineries

·         Process of Manufacture

·         Flow Sheet Diagram

·         List of Raw Materials

·         Availability of Raw Materials

·         Requirement of Staff & Labour

·         Personnel Management

·         Skilled & Unskilled Labour

·         Requirement of Land Area

·         Built up Area

·         Plant Layout.

         

Along with financial details as under:

•        Assumptions for Profitability workings

•        Plant Economics

•        Production Schedule

•        Land & Building

Factory Land & Building

Site Development Expenses

 

•        Plant & Machinery

Indigenous Machineries

Other Machineries (Miscellaneous, Laboratory etc.)

 

•        Other Fixed Assets

Furniture & Fixtures

Pre-operative and Preliminary Expenses

Technical Knowhow

Provision of Contingencies

 

•        Working Capital Requirement Per Month

Raw Material

Packing Material

Lab & ETP Chemical Cost

Consumable Store

 

•        Overheads Required Per Month And Per Annum

Utilities & Overheads (Power, Water and Fuel Expenses etc.)

Royalty and Other Charges

Selling and Distribution Expenses

 

•        Salary and Wages

•        Turnover Per Annum

•        Share Capital

 

Equity Capital

Preference Share Capital

 

•        Annexure 1          ::        Cost of Project and Means of Finance

•        Annexure 2          ::        Profitability and Net Cash Accruals

Revenue/Income/Realisation

Expenses/Cost of Products/Services/Items

Gross Profit

Financial Charges    

Total Cost of Sales

Net Profit After Taxes

Net Cash Accruals

 

•        Annexure 3                    ::        Assessment of Working Capital requirements

Current Assets

Gross Working. Capital

Current Liabilities

Net Working Capital

Working Note for Calculation of Work-in-process

 

•        Annexure 4                    ::        Sources and Disposition of Funds

•        Annexure 5                    ::        Projected Balance Sheets

ROI (Average of Fixed Assets)

RONW (Average of Share Capital)

ROI (Average of Total Assets)

 

•        Annexure 6                    ::        Profitability ratios

D.S.C.R

Earnings Per Share (EPS)

Debt Equity Ratio

 

•        Annexure 7                    ::        Break-Even Analysis

Variable Cost & Expenses

Semi-Var./Semi-Fixed Exp.

Profit Volume Ratio (PVR)

Fixed Expenses / Cost 

B.E.P

 

•        Annexure 8 to 11 ::        Sensitivity Analysis-Price/Volume

Resultant N.P.B.T

Resultant D.S.C.R

Resultant PV Ratio

Resultant DER

Resultant ROI

Resultant BEP

 

•        Annexure 12        ::        Shareholding Pattern and Stake Status

Equity Capital

Preference Share Capital

 

•        Annexure 13        ::        Quantitative Details-Output/Sales/Stocks

Determined Capacity P.A of Products/Services

Achievable Efficiency/Yield % of Products/Services/Items 

Net Usable Load/Capacity of Products/Services/Items   

Expected Sales/ Revenue/ Income of Products/ Services/ Items   

 

•        Annexure 14        ::        Product wise domestic Sales Realisation

•        Annexure 15        ::        Total Raw Material Cost

•        Annexure 16        ::        Raw Material Cost per unit

•        Annexure 17        ::        Total Lab & ETP Chemical Cost

•        Annexure 18        ::        Consumables, Store etc.,

•        Annexure 19        ::        Packing Material Cost

•        Annexure 20        ::        Packing Material Cost Per Unit

•        Annexure 21        ::        Employees Expenses

•        Annexure 22        ::        Fuel Expenses

•        Annexure 23        ::        Power/Electricity Expenses

•        Annexure 24        ::        Royalty & Other Charges

•        Annexure 25        ::        Repairs & Maintenance Exp.

•        Annexure 26        ::        Other Mfg. Expenses

•        Annexure 27        ::        Administration Expenses

•        Annexure 28        ::        Selling Expenses

•        Annexure 29        ::        Depreciation Charges – as per Books (Total)

•        Annexure 30        ::        Depreciation Charges – as per Books (P & M)

•        Annexure 31        ::        Depreciation Charges - As per IT Act WDV (Total)

•        Annexure 32        ::        Depreciation Charges - As per IT Act WDV (P & M)

•        Annexure 33        ::        Interest and Repayment - Term Loans

•        Annexure 34        ::        Tax on Profits

•        Annexure 35        ::        Projected Pay-Back Period And IRR

In order to get our consultancy services to establish a IV fluids, you may visit http://goo.gl/mpnu8y that offers every bit of information regarding subject & Contact us for more details.