Active Pharma Ingredients (API) - Global Market Estimated to Reach US$ 21.9 billion by 2023: Investment Opportunity for Startups and Entrepreneurs, Medications, Drugs and Pharmaceuticals, Cephalexin Monohydrate, Ampicilin Trihydrate, Ibuprofen Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics, Production Schedule, Working Capital Requirement, Plant Layout, Process Flow Sheet, Cost of Project, Projected Balance Sheets, Profitability Ratios, Break Even Analysis

Active Pharmaceutical Ingredients are portions of any drug, which are active. Thus, depending on the drug’s administered dosage, the reactions and results differ. Certain drugs are comprised of more than one kind of API. APIs of good quality are essential for the manufacture of effective and safe medicines. Manufacturers use certain standards to determine how strong the API is in each drug. However, the standard can vary widely from one brand to another. One brand might use one test, another a different one.

On the basis of type of manufacturers of active pharmaceutical ingredient, the market can be categorized as in-house active pharmaceutical ingredient manufacturing and active pharmaceutical contract manufacturing. The in-house active pharmaceutical ingredient manufacturing leads the active pharmaceutical ingredient market by type of manufacturer category. In addition, the in-house manufacturing is continuously witnessing decline in the segment due to reduced profitability and high research and development cost. On the basis of type of active pharmaceutical ingredient, the market can be categorized as biological active pharmaceutical ingredients, and synthetic chemical active pharmaceutical ingredients.

An active ingredient (AI) is the substance in a pharmaceutical drug or a pesticide that is biologically active. The similar terms active pharmaceutical ingredient (API) and bulk active are also used in medicine, and the term active substance may be used for pesticide formulations. Some medications and pesticide products may contain more than one active ingredient. A dosage form: the API, which is the drug itself; and an excipient, which is the substance of the tablet, or the liquid the API is suspended in, or other material that is pharmaceutically inert. Drugs are chosen primarily for their active ingredients. The Indian pharmaceutical industry also needs to take advantage of the recent advances in biotechnology and information technology. The future of the industry will be determined by how well it markets its products to several regions and distributes risks, its forward and backward integration capabilities, its R&D, its consolidation through mergers and acquisitions, co-marketing and licensing agreements.

Uses and Applications

API like Cephalexin is used to treat a number of infections including: otitis media, streptococcal pharyngitis, bone and joint infections, pneumonia, cellulitis, and urinary tract infections. It may be used to prevent bacterial endocarditis. Amoxicillin is used in the treatment of a number of infections, including acute otitis media, Streptococcal pharyngitis, pneumonia, skin infections, urinary-tract infections, Salmonella, lyme disease, and chlamydia infections. It is also used to prevent bacterial endocarditis in high-risk people who are having dental work done, to prevent strep pneumococus infections in those without spleens, and for both the prevention and the treatment of anthrax. Ibuprofen is used primarily for fever, pain, dysmenorrhea and inflammatory diseases such asrheumatoid arthritis. It is also used for pericarditis and patent ductus arteriosus.

Market Survey

The demand for pharmaceutical products in India is significant and is driven by low drug penetration, rising middle-class & disposable income, increased government & private spending on healthcare infrastructure, increasing medical insurance penetration etc. India based pharmaceutical companies are not only catering to the domestic market and fulfilling the country’s demands, they are also exporting to around 220 countries. They are exporting high quality, low cost drugs to countries such as the US, Kenya, Malaysia, Nigeria, Russia, Singapore, South Africa, Ukraine, Vietnam, and more.

India has the world's third largest active pharmaceutical ingredients (API) for the industry valued at a little less than USD 2 bn. Top 5 API producers account for approximately 6.5 %.The growth has been driven by many factors, such as legislative reforms, growth in contract manufacturing and outsourcing, value added foreign acquisitions and joint ventures and India's acu-men and expertise in reverse engineering of patented drug molecules. India has, in the meantime,  been trying to comply with the World Trade Organization's Trade Related Intellectual Property Agreement (TRIPs) obligations.

Production of active pharmaceutical ingredients is a highly sophisticated and technically demanding process. The global active pharmaceutical ingredient market is surging due to the increased demand for pharmaceutical drugs, which in turn is driven by aging population, increasing prevalence of chronic diseases such as cancer, diabetes, cardiovascular, neurological and infectious diseases among others. The global Active Pharmaceutical Ingredient market for was valued at US$ 12.9 bn in 2014 and is estimated to reach US$ 21.9 billion by 2023 at a CAGR of 6.3% from 2015 to 2023.

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