Home » Profiles » Quinine Sulphate From Cinchona Bark - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities

Quinine Sulphate From Cinchona Bark - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities

Quinine sulfate belongs to the anti-malarial category of drugs and it is the sulfate of an alkaloid obtained from the bark of species of Cinchona. The bark of cinchona produces several alkaloids. The most important alkaloid, quinine, has certain febrifuge properties. Of 38 species of cinchona, four species have economic value for the production of quinine: C. calisaya, C. legeriana, C. officianalis and C. succirubra. It contains not less than 99 percent and not more than 101 percent of total alkaloid salt, calculated as (C20H24N2O2)2•H2SO4, on the anhydrous basis. Cinchona trees remain the only practical source of quinine. Cinchona is a genus of tropical evergreen trees and shrubs, belonging to the family Rubiaceae. Not all species of cinchona can be used to produce quinine. Quinine is the chief alkaloid of cinchona bark (known as 'Fever Bark'), a tree found in South America. It is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike quinine, is an anti-arrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine. In 1820, Pelletier and Caventou isolated quinine and cinchonine from cinchona. Though it has been synthesized in the lab, the bark of the cinchona tree is the only known natural source of quinine. Even today, quinine is obtained entirely from the natural sources due to the difficulties in synthesizing the complex molecule. The Indian pharmaceutical industry is the fourth largest in the world in terms of volume of output and thirteenth in domestic demand. The growth has been driven by many factors, such as legislative reforms, growth in contract manufacturing and outsourcing, value added foreign acquisitions and joint ventures and India's acu-men and expertise in reverse engineering of patented drug molecules. India has, in the meantime, been trying to comply with the World Trade Organization's Trade Related Intellectual Property Agreement (TRIPs) obligations. There is a very good scope for new entrepreneurs in this sector.
Plant capacity: 60 MT/AnnumPlant & machinery: 497 Lakhs
Working capital: -T.C.I: Cost of Project : 747 Lakhs
Return: 45.00%Break even: 54.00%
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  • One Lac / Lakh / Lakhs is equivalent to one hundred thousand (100,000)
  • One Crore is equivalent to ten million (10,000,000)
  • T.C.I is Total Capital Investment
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